Protein Alignment Chd1 and LOC1273471

DIOPT Version :10

• Sequence 1: NP_001245851.1
• Gene: Chd1 / 33505
• FlyBaseID: FBgn0250786
• Length: 1900
• Species: Drosophila melanogaster
• Sequence 2: XP_312449.5
• Gene: LOC1273471 / 1273471
• VectorBaseID: AGAMI1_011781
• Length: 1503
• Species: Anopheles gambiae
• Alignment Length: 1481
• Identity: 313/1481 - (21%)
• Similarity: 514/1481 - (34%)
• Gaps: 538/1481 - (36%)

  Fly    74 SSPEPEDKSLSVAGFPPTAAAAQADSKTNGFTDDQEDSSSDGSSGSDSDSDAEGPSDQRNQSINN 138
            :|||.|.:|.:|       |...||:.:|.....|||  .:|.||:::.||.|..| :||:|.::
Mosquito   296 ASPEEEQQSDAV-------ALENADTGSNSKQHRQED--DNGGSGNENQSDVEEGS-KRNESDSD 350

  Fly   139 A-------NTSSSLPKPEQNEEEDNETEAGQQQPASDASADESSDSSANVSPTSSSSSSEEEE-- 194
            |       .:.:|:||     |:.|.....:::..||  :||..|:....:|.::.::.::.|
Mosquito   351 APITRGRNKSKTSIPK-----EKKNTLITRKRRAVSD--SDEEQDTGKPSTPVANGNTDKDSESG 408

  Fly   195 EDYR-PKRTRQARKPPTAAEKSKKAPAPKNKKKTWDSDESDESEDSDDEVSTAQKRKPAATTSRS 258
            .|:. .||.....:...|||:||:..|...|.....:||:...|::|.|.:..|.||
Mosquito   409 SDFEFAKRNTATSRSQRAAERSKRGRAGATKAAAPSADEASNDEEADKEKNDFQTRK-------- 465

  Fly   259 KLAQQQQRRRVKPFSSEDSDDD--DASKRCATRRKGAAVSYKEASEDEATDSED--------LLE 313
                  :|.|::..|:..|.:|  ..|||  .:||    ..|:.:.|...||.:        ||:
Mosquito   466 ------KRTRIRRNSTSSSGEDGKPVSKR--KKRK----QTKKKNSDSEGDSPNKGRKNIRKLLK 518

  Fly   314 FEYDESQAATTAATAEEEEKCETIERILAQRAGKRGCTGNQTTIYAIEENGFDPHAGFDEKQTPD 378
                :|....|...||:||:    ||  .||..:|....||.               :|||.
Mosquito   519 ----KSDLEETTKNAEQEER----ER--KQRIAERQKLYNQV---------------YDEKP--- 555

  Fly   379 AETEAQFLIKWKGWSYIHNTWESEATLRDMKAKGMKKLDNFIKKEKEQAYWRRYAGPEDIDYFEC 443
                                 |...|           ||..:                 :|:.|
Mosquito   556 ---------------------EEACT-----------LDQLV-----------------LDFDE- 570

  Fly   444 QLELQHELLKSYNNVDRIIAKGSKPDDGTEEYLCKWQSLPYAESTWEDAALVLRKWQRC---AEQ 505
              |.:..||:    |||.:.|..||                     ..|..:...:..|   .||
Mosquito   571 --ETKEPLLE----VDRKLVKQLKP---------------------HQANGIKFMFDACFESLEQ 608

  Fly   506 FNDRESSKCTPSRHCRVIKYRPKFSRIKNQPEFLSSGLTLRDYQMDGLNWLLHSWCKENSVILAD 570
            .|..:.|.|                                                    |||.
Mosquito   609 MNQSKGSGC----------------------------------------------------ILAH 621

  Fly   571 EMGLGKTIQTICFLYSLFKIHHLYG--PFLCVVPLSTMTAWQREFDLWAPDMNVVTYLGDIKSRE 633
            .||||||:|.:...::|.....|.|  ..|.|.||||:..|..||.:|...:...|   :::..|
Mosquito   622 CMGLGKTLQVVTLAHTLLASADLTGVERILVVCPLSTVLNWANEFHMWMKHVKKGT---EVEVYE 683

  Fly   634 LIQQY-----------EWQFESSKRLKFNCILTTYEIVLK---------DKQFLGTLQWA----- 673
             |.:|           ||..|.      ..::..|::...         .|:...:||.:
Mosquito   684 -ISKYKDNVTRANKLMEWHNEG------GVMIMGYDMFRNLANPTATRIRKKVRESLQTSLIDPG 741

  Fly   674 --ALLVDEAHRLKNDDSLLYKSLKEFDTNHRLLITGTPLQNSLKELWALLHFIMPDKFDTWENFE 736
              .::.||.|.|||:.:.|.:::....|..|:::||||:||::||.:.::.|:.|....|:..:.
Mosquito   742 PELIVCDEGHLLKNEKTSLSQAVNRISTMRRIVLTGTPIQNNMKEYYCMVQFVKPKLLGTYTEYM 806

  Fly   737 VQHGNAEDKG-YTR---------------LHQQLEPYILRRVKKDVEKSLPAKVEQILRVEMTSL 785
            .:..|....| ||.               ||:.|:..:.||....:...||.|:|.::.:::|.|
Mosquito   807 NRFVNPITNGQYTDSTPYDIQLMRKRAHVLHKLLDGCVQRRDYAVLAPFLPPKLEFVVSIKLTPL 871

  Fly   786 QKQYYKWILTKNFDALRKGKRGS-------TSTFLNIVIELKKCCNHAALIR------------- 830
            |...||:.:..     ..|||..       :|...|....|::...|..::|
Mosquito   872 QSTLYKYYMEN-----MAGKRNDDDPTLKRSSMLFNDFQNLQRIWTHPRVLRYNSDRYEIKQQRK 931

  Fly   831 ------------------------------PSEFELMGLQQDEALQTLLKG-------------- 851
                                          .||.::..:..|.:......|
Mosquito   932 RDLDSENESEGSMKDFIDDEDTAESTPASSDSESDVQSVHDDSSRDAKSSGDSTSNKRKATVGTR 996

  Fly   852 ------------------------------------------SGKLVLLDKLLCRLKETGHRVLI 874
                                                      |||||:|.::|...:..|.::|:
Mosquito   997 STRNNPNFNGGDDDDVIMQKPENPTEWWMQMCPETELDNLEHSGKLVVLMEILKECEAIGDKLLV 1061

  Fly   875 FSQMVRMLDVLADYL----------------QKRHFP--------FQRLDGSIKGEMRRQALDHF 915
            |||.:..|||:..:|                |...:|        :.|||||...:.|..|...|
Mosquito  1062 FSQSLYSLDVIEHFLSLLDENLQKDEDERDEQLSKYPGSWSLGLDYFRLDGSTSIDNRNDACKVF 1126

  Fly   916 NAE-GSQDFCFLLSTRAGGLGINLATADTVIIFDSDWNPQNDLQAQARAHRIGQKNQVNIYRLVT 979
            |.| .::...||:|||||||||||..|:.|:|||..|||.:|:|:..|.:|.||.....|||.:.
Mosquito  1127 NDESNTRARLFLISTRAGGLGINLVAANRVVIFDVSWNPSHDIQSIFRVYRFGQSKPCYIYRFIA 1191

  Fly   980 ARSVEEQIVERAKQKMVLDHLVI--QRMDTTGRTVLDKSGNGHSSNSNPFNKDDLSAILKFGAEE 1042
            ..::||:|.||...|..:...||  |::|                  ..:.::||        :|
Mosquito  1192 MGTMEEKIYERQVTKQAISKRVIDEQQID------------------RHYKENDL--------QE 1230

  Fly  1043 LFKDEQEHDDDLVCDIDEILRRAETRNEDPEMPAD----DLLSAFKVASIAAFEEEPSDSVSKQD 1103
            |::.|.|              .:|.| ..|.:|.|    :||..|. ..|..:.|..| .:..::
Mosquito  1231 LYRYEVE--------------TSEPR-PTPNVPKDRLFAELLKRFD-PLIYKYHEHDS-LLENKE 1278

  Fly  1104 QNAAGEEDDSKDWDDIIPEGFRKAIDDQERAKEMEDLYLPPRRKTAANQNEGKRGAGKGGKGKQQ 1168
            :....||:....|::.          :||:.:       ||   ..|....|..|.|
Mosquito  1279 EETLNEEERKAAWEEF----------EQEKNR-------PP---MPAYGTSGMLGIG-------- 1315

  Fly  1169 ADDSGGDSDYELGSDGSGDDGRPRKRGRPTMKEKITGFTDAELRRFIRSYKKFPAPLHRMEAIAC 1233
                        |..|.|.:|       |.......||.:..|.:.:....:...|......|..
Mosquito  1316 ------------GMGGRGVNG-------PVTSSTTFGFRNDVLLKLLHLKAREDNPTFNDATINA 1361

  Fly  1234 DAELQEKPLAELKRLGEMLHDRCVQFLHEHKEEESKTAATDETPGAKQRRARATFSVKLGGVSFN 1298
            ......:.|::..|.||:...:.:..|:                          :.:::.....|
Mosquito  1362 MIPYLMQQLSQQMRDGELTMYKSLWELY--------------------------YKLEVPPQQMN 1400

  Fly  1299 AKKLLACEQELQP------LNEIMPSMP--EERQQWSFNIKTRAPVFDVDW 1341
            .:..:|....:||      :.:::|..|  .::|..:.::.|..||.::.:
Mosquito  1401 QQYTMAYSNTMQPGGGGMVMGQMVPQQPLMGQQQPMAGSVVTGGPVVNMQY 1451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Chd1	NP_001245851.1	CD1_tandem_CHD1-2_like	339..421	CDD:349313	13/81 (16%)
		CD2_tandem	454..508	CDD:349306	10/56 (18%)
		PLN03142	531..>1066	CDD:215601	158/712 (22%)
		CDH1_2_SANT_HL1	1205..1298	CDD:465731	10/92 (11%)
		DUF4208	1521..1610	CDD:464035
LOC1273471	XP_312449.5	None