DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3165 and REX4

DIOPT Version :9

Sequence 1:	NP_001285571.1	Gene:	CG3165 / 33503	FlyBaseID:	FBgn0031484	Length:	351	Species:	Drosophila melanogaster
Sequence 2:	NP_014561.1	Gene:	REX4 / 854075	SGDID:	S000005440	Length:	289	Species:	Saccharomyces cerevisiae

Alignment Length:	210	Identity:	47/210 - (22%)
Similarity:	78/210 - (37%)	Gaps:	53/210 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 MEIDDTQQKETSQL---KVPNDVQEIIPELKPKQNTETCLKEPEAVVNIDWRTRNETTPNRPILK 229
            |::.....||.|:.   |:...|.|..|.   |.||.|.:||| ..|.|...||..:..::.|.|
Yeast    60 MDMVYNMNKEISKHEKDKLEGKVFEFNPN---KANTSTTIKEP-VKVGISEDTRINSNKSKEIGK 120

  Fly   230 ---------------PTEAFAKRKLLRDGDEDDLEEQTPPKRKPDEFRSRRQLFSGCKCAENKRY 279
                           ...|.|:..::.......|:|...|:.|..|:|:   ..||.|
Yeast   121 YIAMDCEFVGVGPEGKESALARISIVNYFGHVVLDEFVKPREKVVEWRT---WVSGIK------- 175

  Fly   280 PPRGVYNLESLYTRIFKIPALSAHQAEADVVMTTKLIQH---YGIDFLAFAEEQA--------IP 333
             |..:.|..:     ||    .|.:..||::....|:.|   :.::.|..:..::        :|
Yeast   176 -PEHMKNAIT-----FK----EAQKKTADILEGRILVGHALKHDLEALMLSHPKSLLRDTSRHLP 230

  Fly   334 FQQVVPLGSPVCRKK 348
            |:::...|.....||
Yeast   231 FRKLYAKGKTPSLKK 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3165	NP_001285571.1	DnaQ	19..>155	CDD:223916
CG3165	NP_001285571.1	TREX1_2	20..173	CDD:99839	1/4 (25%)
REX4	NP_014561.1	REX4_like	122..274	CDD:99847	26/144 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900