DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3165 and REXO1

DIOPT Version :9

Sequence 1:	NP_001285571.1	Gene:	CG3165 / 33503	FlyBaseID:	FBgn0031484	Length:	351	Species:	Drosophila melanogaster
Sequence 2:	XP_011526446.1	Gene:	REXO1 / 57455	HGNCID:	24616	Length:	1382	Species:	Homo sapiens

Alignment Length:	166	Identity:	41/166 - (24%)
Similarity:	54/166 - (32%)	Gaps:	48/166 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   165 RAFMEIDDTQQ--------------KETSQLKVPNDVQEI-IPELKPKQNTET-------CLKE- 206
            ||..||..|.|              :||.:..|..||.:: .|..||....:.       |.||
Human   310 RADPEIKATGQPPSKEGLEAEGGGLRETKETAVQCDVGDLQPPPAKPASPAQVQSSQDGGCPKEG 374

  Fly   207 ---------PEAVVNIDWRTRNETTPN----RPILK-------PTEAFAKRKLLR-DGDEDDLEE 250
                     |.|....|.....:.|.:    ||:.|       |..:..:||..| :|.:.....
Human   375 KPKKKKTGAPPAPSCKDGAQGKDKTKDKGRGRPVEKPRADKKGPQASSPRRKAERPEGTKKKPSS 439

  Fly   251 QTP----PKRKPDEFRSRRQLFSGCKCAENKRYPPR 282
            .||    .|.:||....|....||.......|.|||
Human   440 ATPVATSGKGRPDRPARRPSPTSGDSRPAAGRGPPR 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3165	NP_001285571.1	DnaQ	19..>155	CDD:223916
CG3165	NP_001285571.1	TREX1_2	20..173	CDD:99839	4/7 (57%)
REXO1	XP_011526446.1	EloA-BP1	802..962	CDD:292495
REXO1	XP_011526446.1	REX1_like	1070..1203	CDD:99848
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900