DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3165 and Isg20l2

DIOPT Version :9

Sequence 1:	NP_001285571.1	Gene:	CG3165 / 33503	FlyBaseID:	FBgn0031484	Length:	351	Species:	Drosophila melanogaster
Sequence 2:	NP_001007742.1	Gene:	Isg20l2 / 361977	RGDID:	1359413	Length:	369	Species:	Rattus norvegicus

Alignment Length:	402	Identity:	72/402 - (17%)
Similarity:	114/402 - (28%)	Gaps:	186/402 - (46%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 PNDAVAEHAEEQPKISTFAVLDLETTNLPAYRNNRVSITEL--CIYAFEAALLKKKKKEQDQDEQ 65
            |...|::...|.||....:.:|              ||:::  |:...:.|...|:..||.:|::
  Rat    46 PPSKVSKLNSEPPKKGETSRVD--------------SISKILSCLKKKKEAAASKRDSEQSKDKK 96

  Fly    66 QEL----PAAPRVLHKLNVLFQPSMVVDPEAERITGLSNYLLERESQLDTDAAQLIVSFLKHLPS 126
            ..|    ||             ||...|....:|                   .|:..|...||.
  Rat    97 ASLSWLTPA-------------PSKKTDSVVAKI-------------------DLLGEFQSALPK 129

  Fly   127 PVCLVAHNGWGFDFPILRQAFEKLNIELP--QSLTCVDSLRAFMEIDDTQQKETSQLKVP---ND 186
            |                ::..:|...:.|  :.:...:|.:       ||.|:....|.|   |.
  Rat   130 P----------------KRRTQKKGSKKPLKKKIATENSTQ-------TQSKDKGSNKKPLKKNA 171

  Fly   187 VQEIIPELKPKQNTETCLKEPE----------------------------AVVN----------- 212
            ||. ..:.:|:   :.|.|.|:                            ::||
  Rat   172 VQN-STQAQPE---DKCPKVPQSLPRKMVAIDCEMVGTGPKGRVSSLARCSIVNYNGDVLYDEYI 232

  Fly   213 ------IDWRTR----------NET---TPNRPIL-----------------KPTEAFAKRKLLR 241
                  :|:|||          |.|   |....||                 |..:.|..:.|.|
  Rat   233 RPPCYIVDYRTRWSGIRKCHMVNATPFKTARSQILKILSGKVVVGHAIHNDYKALQYFHPKSLTR 297

  Fly   242 DGDEDDLEEQTPPKRKPDEFRSRRQLFSGCKCAENKRYPPRGVYNLESLYTRIFK---IPALSAH 303
            |..:..|     ..||.|             |.||.      ..:|:.|..::..   ...||.|
  Rat   298 DTSQIPL-----LNRKAD-------------CPENV------TLSLKHLTKKLLSRDIQTGLSGH 338

  Fly   304 QAEADVVMTTKL 315
            .:..|...|.:|
  Rat   339 SSVEDAQATLEL 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3165	NP_001285571.1	DnaQ	19..>155	CDD:223916	22/141 (16%)
CG3165	NP_001285571.1	TREX1_2	20..173	CDD:99839	24/160 (15%)
Isg20l2	NP_001007742.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	36..68		6/35 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	80..107		8/39 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	125..188		17/89 (19%)
		ISG20	196..352	CDD:99852	31/179 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0847
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900