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Protein Alignment CG3165 and TREX1

DIOPT Version :9

Sequence 1:	NP_001285571.1	Gene:	CG3165 / 33503	FlyBaseID:	FBgn0031484	Length:	351	Species:	Drosophila melanogaster
Sequence 2:	NP_338599.1	Gene:	TREX1 / 11277	HGNCID:	12269	Length:	314	Species:	Homo sapiens

Alignment Length:	329	Identity:	78/329 - (23%)
Similarity:	114/329 - (34%)	Gaps:	112/329 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 ISTFAVLDLETTNLPAYRNNRVSITELCIYAFEAALLKKKKKEQDQDEQQELPAAPRVLHKLNVL 81
            :.|....|:|.|.||.   ::..:||||:.|.....|  :.....|.....:|..|||:.||::.
Human    11 MQTLIFFDMEATGLPF---SQPKVTELCLLAVHRCAL--ESPPTSQGPPPTVPPPPRVVDKLSLC 70

  Fly    82 FQPSMVVDPEAERITGLSNYLLERESQ--LDTDAAQLIVSFLKHLPSPVCLVAHNGWGFDFPILR 144
            ..|.....|.|..|||||..:|....:  .|.:.|.|:::||:..|.|.|||||||..:|||:|:
Human    71 VAPGKACSPAASEITGLSTAVLAAHGRQCFDDNLANLLLAFLRRQPQPWCLVAHNGDRYDFPLLQ 135

  Fly   145 QAFEKLNIELPQSLT---CVDSLRAFMEIDDTQQKETSQLKVPNDVQEIIPELKPKQNTETCLKE 206
            .....|.  |..:|.   ||||:                                     |.||.
Human   136 AELAMLG--LTSALDGAFCVDSI-------------------------------------TALKA 161

  Fly   207 PEAVVNIDWRTRNETTPNRPILKPTEAFAKRKLLRDGDEDDLEEQTPPKRKPDEFRSRRQLFSGC 271
                                                     ||..:.|
Human   162 -----------------------------------------LERASSP----------------- 168

  Fly   272 KCAENKRYPPRGVYNLESLYTRIFKIPALSAHQAEADVVMTTKLIQHYGIDFLAFAEEQAIPFQQ 336
                 ..:.||..|:|.|:|||::......:|.||.||:....:.|......|.:.:..|.||..
Human   169 -----SEHGPRKSYSLGSIYTRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGT 228

  Fly   337 VVPL 340
            :.|:
Human   229 IRPM 232

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.