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Protein Alignment gammaTub23C and TUBB2B

DIOPT Version :10

Sequence 1:	NP_476804.1	Gene:	gammaTub23C / 33501	FlyBaseID:	FBgn0260639	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_821080.1	Gene:	TUBB2B / 347733	HGNCID:	30829	Length:	445	Species:	Homo sapiens

Alignment Length:	457	Identity:	156/457 - (34%)
Similarity:	268/457 - (58%)	Gaps:	22/457 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EIITLQLGQCGNQIGFEFWKRLCLEHGISPSGVLEDFANDGLDRKDVFFYQADDDHYIPRAVLLD 68
            ||:.:|.||||||||.:||:.:..||||.|:|.....::..|:|.:|::.:|..:.|:|||:|:|
Human     3 EIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVD 67

  Fly    69 LEPRVINTIMGSVYSKLYNPENVYLSKHGGGAGNNWASG-YSQGEKLQEEVFDIIDREADGSDSL 132
            |||..::::....:.:::.|:|....:  .|||||||.| |::|.:|.:.|.|::.:|::..|.|
Human    68 LEPGTMDSVRSGPFGQIFRPDNFVFGQ--SGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCL 130

  Fly   133 EGFILCHSIAGGTGSGMGSFIMERLADRYPKKLIQTFSVFPNQDEISDVVVQPYNSMLTLKRLTT 197
            :||.|.||:.||||||||:.::.::.:.||.:::.||||.|: .::||.||:|||:.|::.:|..
Human   131 QGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPS-PKVSDTVVEPYNATLSVHQLVE 194

  Fly   198 AADSVVVLDNTALNRIACDRLHIQNPSFSQINNLVSTIMSVSTTTLRYPSYMNNNLIGLTAPLIP 262
            ..|....:||.||..|....|.:..|::..:|:|||..||..||.||:|..:|.:|..|...::|
Human   195 NTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVP 259

  Fly   263 TPQLHFLMTGYTPLTSDSDIHTQQLVNVRKTTVLDVMRRLLQPKNMMVSTGPDKSNHHCYISILN 327
            .|:|||.|.|:.||||..   :||   .|..||.::.:::...||||.:..|   .|..|:::..
Human   260 FPRLHFFMPGFAPLTSRG---SQQ---YRALTVPELTQQMFDSKNMMAACDP---RHGRYLTVAA 315

  Fly   328 IIQGEVDPTQVHKSLQRIRDRKMAQFIPWGPTSIQVALSRSSPYVQSNHRVSGLMLANHTSICSL 392
            |.:|.:...:|.:.:..::::..:.|:.|.|.:::.|:....|   ...::|...:.|.|:|..|
Human   316 IFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP---RGLKMSATFIGNSTAIQEL 377

  Fly   393 FERALNQYDKLRKRGAFLDQFRREDIFKDDLNELDESRETVDCLV---QEYEAATREDYMQFSVK 454
            |:|...|:..:.:|.|||..:..|.:   |..|..|:...::.||   |:|:.||.::..:|..:
Human   378 FKRISEQFTAMFRRKAFLHWYTGEGM---DEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEE 439

  Fly   455 RG 456
            .|
Human   440 EG 441

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.