Protein Alignment Rrp1 and Apex2

DIOPT Version :10

• Sequence 1: NP_001137776.1
• Gene: Rrp1 / 33500
• FlyBaseID: FBgn0004584
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: XP_006529054.1
• Gene: Apex2 / 77622
• MGIID: 1924872
• Length: 526
• Species: Mus musculus
• Alignment Length: 329
• Identity: 98/329 - (29%)
• Similarity: 151/329 - (45%)
• Gaps: 84/329 - (25%)

  Fly   454 LKICSWNVAGLRAWLKKDGL-------------QLIDLEEPDIFCLQETKCAN----------DQ 495
            |::.|||:.|:|:.|:  ||             :::|..:.||.||||||..:          |.
Mouse     2 LRVVSWNINGIRSPLQ--GLACQEPSSCPTALRRVLDELDADIVCLQETKVTSEHSRIQDLYGDV 64

  Fly   496 LPEEVTRLPGYHPYWLC--MPGGYAGVAIYSK--IMPIHVEYGI--------------GN-EEF- 540
            |.|.:..:.||:.|:..  ...||:|||.:.|  ..|:..|.|:              || :||
Mouse    65 LTEPLAIVEGYNSYFSFSRSRSGYSGVATFCKDSATPVAAEEGLSGVFATLNGDIGCYGNMDEFT 129

  Fly   541 -------DDVGRMITAEY--------EK-FYLINVYVPNSG-RKLVNLEPRMRWEKLFQAYVKKL 588
                   |..||.:..::        || ..|||||.|::. .|...|..:||:.:|.|...:.|
Mouse   130 QEELRVLDSEGRALLTQHKIRTLEGKEKTLTLINVYCPHADPGKPERLTFKMRFYRLLQMRAEAL 194

  Fly   589 DAL-KPVVICGDMNVSHMPID----------LENPKNNTKNAGFTQEERDKMTELLGLGFVDTFR 642
            .|. ..|:|.||:|.:|.|||          .|:|.....: |......|:....:|| |:|::|
Mouse   195 LAAGSHVIILGDLNTAHRPIDHCDASSLECFEEDPGRKWMD-GLLSNPGDEAGPHIGL-FMDSYR 257

  Fly   643 HLYPDRKGAYTFWTYMANARARNVGWRLDY-----CLVSERFVPKVVEHEIRSQCLGSDHCPITI 702
            :|:|.::.|:|.|:.::.||..|.|.||||     .||.:.|....:..|:    :||||||:..
Mouse   258 YLHPKQQRAFTCWSVVSGARHLNYGSRLDYVLGDRALVIDTFQASFLLPEV----MGSDHCPVGA 318

  Fly   703 FFNI 706
            ..|:
Mouse   319 VLNV 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rrp1	NP_001137776.1	PTZ00121	<8..396	CDD:173412
		Ape1-like_AP-endo	454..704	CDD:197321	97/325 (30%)
Apex2	XP_006529054.1	Ape2-like_AP-endo	3..320	CDD:197322	96/324 (30%)
		zf-GRF	473..522	CDD:462017