Protein Alignment Rrp1 and apex2

DIOPT Version :10

• Sequence 1: NP_001137776.1
• Gene: Rrp1 / 33500
• FlyBaseID: FBgn0004584
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: XP_031746216.1
• Gene: apex2 / 448512
• XenbaseID: XB-GENE-1012054
• Length: 546
• Species: Xenopus tropicalis
• Alignment Length: 336
• Identity: 101/336 - (30%)
• Similarity: 150/336 - (44%)
• Gaps: 85/336 - (25%)

  Fly   435 TTVTLDKDAFALPADKEF-NLKICSWNVAGLRAWLKKDGL-QLIDLEEPDIFCLQETKCANDQLP 497
            |||.:::.  :.|.|... ::||.|||:.|:||  .:.|| :.:|..:.||.||||||...|.|.
 Frog    12 TTVGVNEK--STPGDATAGSMKIVSWNINGIRA--TRVGLKETLDSLDADIICLQETKVTRDLLD 72

  Fly   498 EEVTRLPGYHPYWLCMPG--GYAGVAIY--SKIMPIHVEYGI--------------GN-EEF--- 540
            |....:.||:.|:....|  ||:|||.:  |...|...|.|:              || |||
 Frog    73 EPSAIVEGYNSYFSFSRGRSGYSGVATFCKSSTTPWAAEEGLSGMLCNHTGSIGCYGNTEEFLEE 137

  Fly   541 -----DDVGRMITAEY---------EKFYLINVYVPNSG-----RKLVNLEPRMRWEKLFQAYVK 586
                 |..||.:..::         |...:||||.|.:.     ||..    ::|:.:|.|.
 Frog   138 ELQSLDQEGRAVLTQHRIRNCEGKEETLTVINVYCPRADPEKPERKTY----KLRFYRLLQT--- 195

  Fly   587 KLDALKP----VVICGDMNVSHMPI------DLENPKNNTKNAGFTQ--------EERDKMTELL 633
            :.:|:..    |:|.||:|.||.|:      |||..:.|.......|        ::.|..|...
 Frog   196 RAEAILQKGGHVIILGDVNTSHRPLDHCDPTDLETFEENPGRQWLNQFLGDPVPSQKGDSETGTP 260

  Fly   634 GLG----FVDTFRHLYPDRKGAYTFWTYMANARARNVGWRLDYC-----LVSERFVPKVVEHEIR 689
            ..|    |.|:||:.:|.::.|:|.|...:.||..|.|.|:||.     ||...|:..::..|:.
 Frog   261 PSGGSGRFYDSFRYFHPTQRNAFTCWCSASGARQTNYGTRIDYILGNSELVEREFLDSIIMPEVE 325

  Fly   690 SQCLGSDHCPI 700
                ||||||:
 Frog   326 ----GSDHCPV 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rrp1	NP_001137776.1	PTZ00121	<8..396	CDD:173412
		Ape1-like_AP-endo	454..704	CDD:197321	96/316 (30%)
apex2	XP_031746216.1	Ape2-like_AP-endo	31..336	CDD:197322	96/315 (30%)
		zf-GRF	490..537	CDD:480736