| Sequence 1: | NP_001137776.1 | Gene: | Rrp1 / 33500 | FlyBaseID: | FBgn0004584 | Length: | 706 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_055296.2 | Gene: | APEX2 / 27301 | HGNCID: | 17889 | Length: | 518 | Species: | Homo sapiens |
| Alignment Length: | 317 | Identity: | 100/317 - (31%) |
|---|---|---|---|
| Similarity: | 146/317 - (46%) | Gaps: | 81/317 - (25%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 454 LKICSWNVAGLRAWLKKDGLQ------------LIDLEEPDIFCLQETKCANDQLPEEVTRLPGY 506
Fly 507 HPYWLCM--PGGYAGVAIYSK--IMPIHVEYGI--------------GN-EEF--------DDVG 544
Fly 545 RMITAEY--------EK-FYLINVYVPNS--GR--KLVNLEPRMRWEKLFQAYVKKLDAL-KPVV 595
Fly 596 ICGDMNVSHMPIDLENPKNNTKNAGFTQEE--RDKMTELL-GLG---------FVDTFRHLYPDR 648
Fly 649 KGAYTFWTYMANARARNVGWRLDY-----CLVSERFVPKVVEHEIRSQCLGSDHCPI 700 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Rrp1 | NP_001137776.1 | RecX | 15..>217 | CDD:294607 | |
| RR_TM4-6 | <314..>388 | CDD:283990 | |||
| Ape1-like_AP-endo | 454..704 | CDD:197321 | 100/317 (32%) | ||
| APEX2 | NP_055296.2 | Ape2-like_AP-endo | 3..311 | CDD:197322 | 99/316 (31%) |
| SPOR | <347..>449 | CDD:331908 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 355..407 | ||||
| Required for the colocalization with PCNA in nuclear foci in presence of oxidative-induced DNA damaging agents | 390..397 | ||||
| zf-GRF | 467..514 | CDD:284302 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG0708 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R72 |
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.840 | |||||