DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rrp1 and apn2

DIOPT Version :9

Sequence 1:	NP_001137776.1	Gene:	Rrp1 / 33500	FlyBaseID:	FBgn0004584	Length:	706	Species:	Drosophila melanogaster
Sequence 2:	NP_595522.1	Gene:	apn2 / 2540679	PomBaseID:	SPBC3D6.10	Length:	523	Species:	Schizosaccharomyces pombe

Alignment Length:	301	Identity:	87/301 - (28%)
Similarity:	140/301 - (46%)	Gaps:	57/301 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   454 LKICSWNVAGLR------AWLKKDGLQLIDLE-EPDIFCLQETKCANDQLPEEVTRLPGYHPYWL 511
            ::|.||||.|::      .|.||:..:.|..| :.|:.|:||.|...|..|::...:.|:..|:.
pombe     1 MRILSWNVNGIQNPFNYFPWNKKNSYKEIFQELQADVICVQELKMQKDSFPQQYAVVEGFDSYFT 65

  Fly   512 C--MPGGYAGVAIYSK---IMPIHVEYGI-----------------GNEE--------------- 539
            .  :..||:||..|.|   .:|:..|.||                 .:|:
pombe    66 FPKIRKGYSGVGFYVKKDVAIPVKAEEGITGILPVRGQKYSYSEAPEHEKIGFFPKDIDRKTANW 130

  Fly   540 FDDVGRMITAEYEKFYLINVYVP-NSGRKLVNLEPRMRWEKLFQAYVKKL--DALKPVVICGDMN 601
            .|..||.|..:::.|.||.||.| |||..  .||.|..:.|..:..:::|  :..:.:::.||:|
pombe   131 IDSEGRCILLDFQMFILIGVYCPVNSGEN--RLEYRRAFYKALRERIERLIKEGNRKIILVGDVN 193

  Fly   602 VSHMPIDLENPKNNTKNA--GFTQEERDKMTEL-----LGLGFVDTFRHLYPDRKGAYTFWTYMA 659
            :...|||..:.|:..:.:  ....|.|..:.:|     ||| .:|..|..:|.|||.:|.|....
pombe   194 ILCNPIDTADQKDIIRESLIPSIMESRQWIRDLLLPSRLGL-LLDIGRIQHPTRKGMFTCWNTRL 257

  Fly   660 NARARNVGWRLDYCLVSERFVPKVVEHEIRSQCLGSDHCPI 700
            |.|..|.|.|:||.|.:...:|.|.:.:|.::.:||||||:
pombe   258 NTRPTNYGTRIDYTLATPDLLPWVQDADIMAEVMGSDHCPV 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rrp1	NP_001137776.1	RecX	15..>217	CDD:294607
		RR_TM4-6	<314..>388	CDD:283990
		Ape1-like_AP-endo	454..704	CDD:197321	87/301 (29%)
apn2	NP_595522.1	Ape2-like_AP-endo	2..302	CDD:197322	87/300 (29%)
apn2	NP_595522.1	zf-GRF	456..513	CDD:284302
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	100	1.000	Domainoid score	I1830
eggNOG	1	0.900	-	-		E1_COG0708
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto101461
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R72
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840