| Sequence 1: | NP_001137776.1 | Gene: | Rrp1 / 33500 | FlyBaseID: | FBgn0004584 | Length: | 706 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_033817.1 | Gene: | Apex1 / 11792 | MGIID: | 88042 | Length: | 317 | Species: | Mus musculus |
| Alignment Length: | 350 | Identity: | 165/350 - (47%) |
|---|---|---|---|
| Similarity: | 209/350 - (59%) | Gaps: | 56/350 - (16%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 373 PARGRKKAAAKAEEPDVDEESGSKSMLAEQSGCGGAAVLKSLQTMLNFCFPATKKAKKAETKTTV 437
Fly 438 TLDKDAF--------------ALPADKEFNLKICSWNVAGLRAWLKKDGLQLIDLEEPDIFCLQE 488
Fly 489 TKCANDQLPEEVTRLPGY-HPYWLCMPG---GYAGVAIYSKIMPIHVEYGIGNEEFDDVGRMITA 549
Fly 550 EYEKFYLINVYVPNSGRKLVNLEPRMRWEKLFQAYVKKLDALKPVVICGDMNVSHMPIDLENPKN 614
Fly 615 NTKNAGFTQEERDKMTELL-GLGFVDTFRHLYPDRKGAYTFWTYMANARARNVGWRLDYCLVSER 678
Fly 679 FVPKVVEHEIRSQCLGSDHCPITIF 703 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Rrp1 | NP_001137776.1 | RecX | 15..>217 | CDD:294607 | |
| RR_TM4-6 | <314..>388 | CDD:283990 | 8/14 (57%) | ||
| Ape1-like_AP-endo | 454..704 | CDD:197321 | 144/254 (57%) | ||
| Apex1 | NP_033817.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..58 | 20/91 (22%) | |
| Necessary for interaction with YBX1, binding to RNA, association together with NPM1 to rRNA, endoribonuclease activity on abasic RNA and localization in the nucleoli. /evidence=ECO:0000250 | 2..32 | 15/61 (25%) | |||
| Nuclear localization signal (NLS). /evidence=ECO:0000250 | 8..12 | 2/3 (67%) | |||
| Necessary for interaction with NPM1 and for efficient rRNA binding. /evidence=ECO:0000250 | 22..32 | 5/9 (56%) | |||
| Ape1-like_AP-endo | 61..315 | CDD:197321 | 144/254 (57%) | ||
| Nuclear export signal (NES). /evidence=ECO:0000250 | 63..79 | 13/15 (87%) | |||
| Mitochondrial targeting sequence (MTS). /evidence=ECO:0000250 | 288..317 | 13/26 (50%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C167840828 | |
| Domainoid | 1 | 1.000 | 279 | 1.000 | Domainoid score | I1677 |
| eggNOG | 1 | 0.900 | - | - | E1_COG0708 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0005771 | |
| OrthoInspector | 1 | 1.000 | - | - | oto93958 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_101139 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR22748 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R72 |
| SonicParanoid | 1 | 1.000 | - | - | X5491 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| 12 | 11.730 | |||||