DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rbp9 and elavl2

DIOPT Version :9

Sequence 1:	NP_001259974.1	Gene:	Rbp9 / 33498	FlyBaseID:	FBgn0010263	Length:	684	Species:	Drosophila melanogaster
Sequence 2:	XP_012819022.1	Gene:	elavl2 / 594913	XenbaseID:	XB-GENE-491749	Length:	390	Species:	Xenopus tropicalis

Alignment Length:	373	Identity:	222/373 - (59%)
Similarity:	267/373 - (71%)	Gaps:	18/373 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 AAVGQATANNAASNNNNNNNNTNNNNNNNATANNNNNNEPDPKTNLIVNYLPQTMSQDEIRSLFV 131
            ||:....:|....||..|..||.||.::...::|..    |.|||||||||||.|:|:|::|||.
Frog    28 AAMETQLSNGPTCNNTANCPNTINNCSSPVESSNTE----DSKTNLIVNYLPQNMTQEELKSLFG 88

  Fly   132 SFGEVESCKLIRDKVT-GQSLGYGFVNYVKQEDAEKAINALNGLRLQNKTIKVSIARPSSESIKG 195
            |.||:|||||:|||:| |||||||||||:..:|||||||.|||||||.||||||.|||||.||:.
Frog    89 SIGEIESCKLVRDKITEGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRD 153

  Fly   196 ANLYVSGLPKNMTQSDLESLFSPYGKIITSRILCDNITGLSKGVGFIRFDQRFEADRAIKELNGT 260
            ||||||||||.|||.:||.|||.||:|||||||.|.:||:|:||||||||:|.||:.|||.|||.
Frog   154 ANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ 218

  Fly   261 TPKNSTEPITVKFANNPSSNKNSMQPLAAYIAPQNTRGGRAFPANAAAGAAAAAAAAAIHPNAGR 325
            .|..:|||||||||||||...|.......|.:|     .|.:|...|..|........::.   .
Frog   219 KPPGATEPITVKFANNPSQKVNHTILSQLYQSP-----NRRYPGPLAQQAQRFRLDNLLNM---A 275

  Fly   326 YSSVISRYSPLTSDLITNGMIQGNTI---ASSGWCIFVYNLAPDTEENVLWQLFGPFGAVQSVKV 387
            |..:.||:||:|.|.:|:  :.|...   |.:||||||||||||.:|::|||:|||||||.:|||
Frog   276 YGGIKSRFSPMTIDGMTS--LAGINFPGHAGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKV 338

  Fly   388 IRDLQSNKCKGFGFVTMTNYEEAVLAIQSLNGYTLGNRVLQVSFKTNK 435
            |||..:||||||||||||||:||.:||.|||||.||:|||||||||:|
Frog   339 IRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTSK 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbp9	NP_001259974.1	ELAV_HUD_SF	107..438	CDD:273741	211/333 (63%)
		RRM1_Hu	109..186	CDD:241094	60/77 (78%)
		RRM2_Hu	196..274	CDD:241096	56/77 (73%)
		RRM3_Hu	355..432	CDD:240823	60/76 (79%)
elavl2	XP_012819022.1	ELAV_HUD_SF	64..389	CDD:273741	211/333 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	121	1.000	Domainoid score	I5618
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	414	1.000	Inparanoid score	I1795
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D425303at33208
OrthoFinder	1	1.000	-	-		FOG0000313
OrthoInspector	1	1.000	-	-		mtm9409
Panther	1	1.100	-	-	O	PTHR10352
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X326
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.070