DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rbp9 and Elavl1

DIOPT Version :9

Sequence 1:	NP_001259974.1	Gene:	Rbp9 / 33498	FlyBaseID:	FBgn0010263	Length:	684	Species:	Drosophila melanogaster
Sequence 2:	NP_001102318.1	Gene:	Elavl1 / 363854	RGDID:	1308649	Length:	326	Species:	Rattus norvegicus

Alignment Length:	331	Identity:	200/331 - (60%)
Similarity:	241/331 - (72%)	Gaps:	28/331 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 KTNLIVNYLPQTMSQDEIRSLFVSFGEVESCKLIRDKVTGQSLGYGFVNYVKQEDAEKAINALNG 173
            :||||||||||.|:|:|:||||.|.|||||.|||||||.|.||||||||||..:|||:||:.|||
  Rat    19 RTNLIVNYLPQNMTQEELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAISTLNG 83

  Fly   174 LRLQNKTIKVSIARPSSESIKGANLYVSGLPKNMTQSDLESLFSPYGKIITSRILCDNITGLSKG 238
            ||||:||||||.||||||.||.||||:||||:.|||.|:|.:||.:|:||.||:|.|..||||:|
  Rat    84 LRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRG 148

  Fly   239 VGFIRFDQRFEADRAIKELNGTTPKNSTEPITVKFANNPSSNKNSMQPLAAYIAPQNTRGGRAFP 303
            |.|||||:|.||:.||...||..|..|:||||||||.||:.|||.......|.:|....||
  Rat   149 VAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNMALLSQLYHSPARRFGG---- 209

  Fly   304 ANAAAGAAAAAAAAAIHPNAGRYSSVISRYSPLTSDLIT--NGM-IQGNTIASSGWCIFVYNLAP 365
                          .:|..|.|:     |:||:..|.::  :|: :.||  ||||||||:|||..
  Rat   210 --------------PVHHQAQRF-----RFSPMGVDHMSGISGVNVPGN--ASSGWCIFIYNLGQ 253

  Fly   366 DTEENVLWQLFGPFGAVQSVKVIRDLQSNKCKGFGFVTMTNYEEAVLAIQSLNGYTLGNRVLQVS 430
            |.:|.:|||:|||||||.:||||||..:|||||||||||||||||.:||.|||||.||:::||||
  Rat   254 DADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVS 318

  Fly   431 FKTNKN 436
            |||||:
  Rat   319 FKTNKS 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbp9	NP_001259974.1	ELAV_HUD_SF	107..438	CDD:273741	200/331 (60%)
		RRM1_Hu	109..186	CDD:241094	59/76 (78%)
		RRM2_Hu	196..274	CDD:241096	48/77 (62%)
		RRM3_Hu	355..432	CDD:240823	56/76 (74%)
Elavl1	NP_001102318.1	ELAV_HUD_SF	19..326	CDD:273741	200/331 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	121	1.000	Domainoid score	I5544
eggNOG	1	0.900	-	-		E1_KOG0145
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	416	1.000	Inparanoid score	I1763
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D425303at33208
OrthoFinder	1	1.000	-	-		FOG0000313
OrthoInspector	1	1.000	-	-		mtm8987
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10352
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X326
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.930