DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rbp9 and Elavl2

DIOPT Version :9

Sequence 1:	NP_001259974.1	Gene:	Rbp9 / 33498	FlyBaseID:	FBgn0010263	Length:	684	Species:	Drosophila melanogaster
Sequence 2:	NP_001289146.1	Gene:	Elavl2 / 286973	RGDID:	628611	Length:	388	Species:	Rattus norvegicus

Alignment Length:	369	Identity:	224/369 - (60%)
Similarity:	263/369 - (71%)	Gaps:	22/369 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 AASNNNNNNNNTNNNNNNNATANNNNNNEP-------DPKTNLIVNYLPQTMSQDEIRSLFVSFG 134
            ||.....:|..|.||..|..|..|||.:.|       |.|||||||||||.|:|:|::|||.|.|
  Rat    28 AAMETQLSNGPTCNNTANGPTTVNNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIG 92

  Fly   135 EVESCKLIRDKVTGQSLGYGFVNYVKQEDAEKAINALNGLRLQNKTIKVSIARPSSESIKGANLY 199
            |:|||||:|||:||||||||||||:..:|||||||.|||||||.||||||.|||||.||:.||||
  Rat    93 EIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLY 157

  Fly   200 VSGLPKNMTQSDLESLFSPYGKIITSRILCDNITGLSKGVGFIRFDQRFEADRAIKELNGTTPKN 264
            ||||||.|||.:||.|||.||:|||||||.|.:||:|:||||||||:|.||:.|||.|||..|..
  Rat   158 VSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPG 222

  Fly   265 STEPITVKFANNPSSNKNSMQPLAAYIAPQNTRGGRAFPANAAAGAAAAAAAAAIHPNAGRYSSV 329
            :|||||||||||||...|.......|.:|     .|.:|     |..|..|......|....:..
  Rat   223 ATEPITVKFANNPSQKTNQAILSQLYQSP-----NRRYP-----GPLAQQAQRFRLDNLLNMAYG 277

  Fly   330 ISRYSPLTSDLITNGMIQGNTI---ASSGWCIFVYNLAPDTEENVLWQLFGPFGAVQSVKVIRDL 391
            :.|:||:|.|.:|:  :.|..|   ..:||||||||||||.:|::|||:|||||||.:||||||.
  Rat   278 VKRFSPMTIDGMTS--LAGINIPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDF 340

  Fly   392 QSNKCKGFGFVTMTNYEEAVLAIQSLNGYTLGNRVLQVSFKTNK 435
            .:||||||||||||||:||.:||.|||||.||:|||||||||||
  Rat   341 NTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNK 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbp9	NP_001259974.1	ELAV_HUD_SF	107..438	CDD:273741	212/332 (64%)
		RRM1_Hu	109..186	CDD:241094	60/76 (79%)
		RRM2_Hu	196..274	CDD:241096	56/77 (73%)
		RRM3_Hu	355..432	CDD:240823	60/76 (79%)
Elavl2	NP_001289146.1	ELAV_HUD_SF	65..387	CDD:273741	212/332 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353682
Domainoid	1	1.000	121	1.000	Domainoid score	I5544
eggNOG	1	0.900	-	-		E1_KOG0145
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	416	1.000	Inparanoid score	I1763
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D425303at33208
OrthoFinder	1	1.000	-	-		FOG0000313
OrthoInspector	1	1.000	-	-		mtm8987
orthoMCL	1	0.900	-	-		OOG6_103306
Panther	1	1.100	-	-	O	PTHR10352
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X326
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.760