Protein Alignment lilli and aff3

DIOPT Version :10

• Sequence 1: NP_523464.1
• Gene: lilli / 33496
• FlyBaseID: FBgn0041111
• Length: 1673
• Species: Drosophila melanogaster
• Sequence 2: XP_009302946.1
• Gene: aff3 / 570215
• ZFINID: ZDB-GENE-030219-193
• Length: 1242
• Species: Danio rerio
• Alignment Length: 1426
• Identity: 282/1426 - (19%)
• Similarity: 465/1426 - (32%)
• Gaps: 428/1426 - (30%)

  Fly   415 AASGVTSPGPVKPLKTEKNHSLEKQDSCLENDLELSESEDEQRKKEGRSGGNSSNSSESDSSESG 479
            |..||:...|.:||       :....|.|.:||:||..||::                    :.|
Zfish    61 ARDGVSMRMPSRPL-------VAPHKSMLADDLKLSSDEDDK--------------------DEG 98

  Fly   480 SESSSK---NDLQHHPNHQQHHHQLQQQQQQQQATMQQQQVLQQQHRSQPLTSNGAQNKKFRHEI 541
            ||.::.   ||            :|..|.|||          ||||.
Zfish    99 SEQTTSWADND------------RLSTQHQQQ----------QQQHH------------------ 123

  Fly   542 IARGSNTITGLLSSSGFGSGGNVGPAGVNSNAVVGTGSGSGGTLSSGG-------SSSNKTPSPT 599
                ::|..|.:..|..||.|....:...|::........|.....|.       :.|.:|.||
Zfish   124 ----THTHAGRVRHSSSGSSGTDRSSDWESSSQRSRSPSPGAHTRCGTPTQQRTLNCSTETESP- 183

  Fly   600 ESNKWNLSRFFHKPANQTNSESVSPGNVSMKVPGILPGGAQIIPESIDVTTAIVKNEKNDMAMEE 664
            .|..|.|.|:..|...:..|...:||           ||.:                       :
Zfish   184 PSTHWQLDRWLEKVPKKHQSTDYNPG-----------GGHR-----------------------Q 214

  Fly   665 GEEEDDDEEQQLRYGGGLSVTPVAVKKEAIDAVSEMALGAIPKTQIKRESAETLLSAR-LSDSGT 728
            ..:.|.|.                              |..|.....|||.    |.| .|..|:
Zfish   215 SAKSDCDR------------------------------GPSPGRYWSRESE----SRRDYSPCGS 245

  Fly   729 SASGSSSSSSSSSDSAMGGEVVPMPGPGETLQLPGVPAAITTVMRVQPTQSQKAPPSNSVTLTPI 793
            .........|..:.........|.|.||.:|....||:       |.|:.......|.|.:
Zfish   246 QVPSPKFDYSPRNSPHPSPGYSPCPSPGNSLVQSPVPS-------VCPSPGDSLQGSRSPS---- 299

  Fly   794 LPLPTSPKQRQKKPRKKKAITSAPI---LDSSDDDEP----------------------PPKHPG 833
             ||||.|.:........||:.|..|   :.:|..:.|                      ||.|..
Zfish   300 -PLPTHPPRSPSPSLLSKAVPSQGIYSQVQTSQQESPRHISRPTVASNSGHHPKVRPWVPPDHNA 363

  Fly   834 LDHTAVSVQTQPATDTVKKGRGRPRKQQQSGGSGNLSS----------ASAGSSSQTK-----GP 883
            .....:..:...:.|:..|. .||..|.|...|.:.|:          ..|.:|..|:     .|
Zfish   364 NQRKELRAKDSRSKDSQSKD-SRPGPQHQPFNSKHGSTERSHKDFTHKPEAKNSESTRKQRFNSP 427

  Fly   884 TLTAAKKPLAKTPLAMSRARKR-----EHSSQSSSNGNTPTKKVATPQLVAAPLKPTSNTAGSSS 943
            :.|.:|.||.:.|....:.:.|     :|||:.:...|.||         |.|:..:::.:|.||
Zfish   428 SKTVSKHPLQQRPSISPKPQARTLSTVDHSSEFNHKSNEPT---------AVPVHNSTSKSGHSS 483

  Fly   944 -------------SDEDSSSSAESSSKSSSSSSSSDDTETQNTNCRIVKLNKTGAVQKKALLGSG 995
                         |....|...|::|:||.||.:....:|..::.:....:.:....:..|  ..
Zfish   484 HFSILKSSECGPLSKFKDSLQREANSRSSHSSKNKSFPDTNRSSSKQTSQSSSSPKPRPKL--ED 546

  Fly   996 SSSPSSSGSEAED---QTTRSQVGSGQALAQQLPPYKQLPISQHSQHLSSSDCSSSSGGCTAVCS 1057
            ||.|.:..|:.|.   :..|.....|:|....|     :|..:..:|...::.............
Zfish   547 SSVPRTGHSQKEPKPRERDREVDSRGRAQGVNL-----VPTGKEQRHRRLAEEQVIRRRWVRSSE 606

  Fly  1058 SSSGEED----EGRREKERERK--PKSDKNKINTLTRIFNPKEGGAKKQGQVVIVDLQEEQQQGK 1116
            ...||||    ||.||::|.|:  |:::...:....|   |.......|.:....:|:|::::.:
Zfish   607 EEEGEEDKRTEEGERERKRRRRREPEAEWRAVQPKQR---PHTSQHHTQRECNGPNLEEQRRKKR 668

  Fly  1117 L----DAAAQPSAPQAPPAAPAAIMAKPRMTPTQQQQLGAGLASPARTTTPHLTSLICKIDLSKL 1177
            .    |.:::|....:.|:.|   ::.|..||.            .:.|.|..:|.......|..
Zfish   669 RWSNGDVSSRPYVTDSSPSPP---LSPPTPTPV------------VKPTHPLSSSSSSSFSSSSS 718

  Fly  1178 SRERIMRLKKLTPAQQNGHLTPKDQATNAVHVPNGYAGDTNPAAKVKHE--------HPVK---P 1231
            |.|            .:...:|   ..|...||.....:....:|.:||        ||.:   .
Zfish   719 SSE------------SDSESSP---PRNIAKVPADSTSNKKTVSKSRHEKQNSGSSSHPERSCLS 768

  Fly  1232 EPELDAGYEAKFK----------------P----------------GNVKQEFQLKQERDRDRER 1264
            .||.:.....:.|                |                |.|....:|.:.:......
Zfish   769 TPETEKHSRGRHKLYTLVPFGRTEKSPTIPHRGLKKLVVRIDLCLLGRVPSADELTERQSSSSSV 833

  Fly  1265 ERERERERERDR---EREQPPGRRRKRSSSSSSSPYKEKKRKKEKADQLQMGKELLPVPVLLPSN 1326
            ...:.:|:...:   ..:||||..|.:..:.:....:|.||.....|:             .||:
Zfish   834 SSGKAKEKSSMKHLNHSDQPPGDGRSKRKAENGDLQRENKRNHSCTDK-------------QPSS 885

  Fly  1327 NHERMPNHDRLSYDKLQLLHEDAAAVIGDVSAPNGSPTKKLLA---MSPLPPPPTVT-------- 1380
            .|                 ||.....:.  :..||.......:   :|||.||..:.
Zfish   886 VH-----------------HETEETCVD--NQQNGCQDDYFYSKRPVSPLSPPSNILELSKHSVK 931

  Fly  1381 --------VAPATCNEA------VQTTPPSATA-----------TSAIAPPVPATRLIYRSYFD- 1419
                    ..|...|::      :|.|.|....           .|....|.|...|.||....
Zfish   932 AQHAEKYYTPPEKDNDSTAQKTQIQKTQPKVEVECIGVSGHLQPLSGSRVPPPNLPLHYRGTVPI 996

  Fly  1420 RDVEHPSDDPRKNNQFLQEAINRKHAADLERDSFNQVTLYLEAVVYFLLTADAMERCSSE-QATN 1483
            .||.|.::      .::.||...||.||...|...:...|::|.:.|:....|||....| ::..
Zfish   997 SDVSHHAE------YYMHEAKRLKHRADAMVDKLGKAVNYVDAALSFMECGKAMEEGPLESKSPY 1055

  Fly  1484 TMYKDTLSLIKFISTKFRPYQQQSTTNIQHETHNKVAILSLRCQSLISLKLYKLRRKDCRAIINS 1548
            |||.:|:.||:: :.:.:.:.....:    :...::|:|..||.:|:..::::|::.........
Zfish  1056 TMYAETVELIRY-AMRLKSHAGPGAS----QEDKQLAVLCFRCLALLYWQMFRLKKDHALKYSKV 1115

  Fly  1549 LTDFFRVG---------RGDIANGN-TPSSISPSNSVGSQGSGSNTPPGRI--VPPDIHNMLCKQ 1601
            |.|:|:..         |.|...|. .|:||.   ||...||.:...|..:  :|..||.|....
Zfish  1116 LLDYFKSSPKGPHNPPTRNDSGKGTIPPASIC---SVSIMGSHTGKSPSTVISIPHRIHQMAANH 1177

  Fly  1602 NEFLSYLNSAHELWDQADRLVRTGNHIDFIRELDHENGPLTLHSTMHEVFRYVQAGLKTLR 1662
            ....:.:..::|.|:.||.|.:...  :|...|:...|||||||:|..:.:|.:.||:.:|
Zfish  1178 LNITNSVLYSYEYWEVADTLAKENK--EFFNYLNTLTGPLTLHSSMAHIVQYTRQGLQWIR 1236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lilli	NP_523464.1	AF-4_C	1435..1662	CDD:465894	62/239 (26%)
aff3	XP_009302946.1	AF-4	<25..194	CDD:461550	45/204 (22%)
		PHA03247	<208..427	CDD:223021	52/299 (17%)
		AF-4_C	998..1241	CDD:465894	66/255 (26%)