Protein Alignment NTPase and Entpd2

DIOPT Version :10

• Sequence 1: NP_001259972.1
• Gene: NTPase / 33495
• FlyBaseID: FBgn0024947
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_017447512.1
• Gene: Entpd2 / 64467
• RGDID: 69266
• Length: 568
• Species: Rattus norvegicus
• Alignment Length: 464
• Identity: 118/464 - (25%)
• Similarity: 191/464 - (41%)
• Gaps: 123/464 - (26%)

  Fly   140 VQYAAIIDAGSTGSRVLAYKF-----NRSFIDNKLVLYEELFKERKPGLSSFADNPAEGAHSIKL 199
            ::|..::||||:.:.:..||:     |    |..:|........:..|:||:|::|::...|:..
  Rat    38 LKYGIVLDAGSSHTSMFVYKWPADKEN----DTGIVGQHSSCDVQGGGISSYANDPSKAGQSLVR 98

  Fly   200 LLDEARAFIPKEHWSSTPLVLKATAGLRLLPASKAE---NILNAVRDLFAKSEFSVDMDAVEIMD 261
            .|::|...:|::..:||||.|.||||:|||..:..|   .:|.||....  :::..|.....|:.
  Rat    99 CLEQALRDVPRDRHASTPLYLGATAGMRLLNLTSPEATARVLEAVTQTL--TQYPFDFRGARILS 161

  Fly   262 GTDEGIFSWFTVNFLL---------GRLSKTNQA--AALDLGGGSTQVTFSPTDPDQVPVYDKYM 315
            |.|||:|.|.|.|:||         ||..:..:.  .|:||||.|||:||..|.|.:.|..:.::
  Rat   162 GQDEGVFGWVTANYLLENFIKYGWVGRWIRPRKGTLGAMDLGGASTQITFETTSPSEDPGNEVHL 226

  Fly   316 HEVVTSSKKINVFTHSYLGLG-------LMAAR------HAVFTHGYKKEDTVLESVCVNP-IIA 366
            .   ...:...|:|||:|..|       |:|:.      |..:..||..: .:|:.|..:| .:.
  Rat   227 R---LYGQHYRVYTHSFLCYGRDQILLRLLASALQIHRFHPCWPKGYSTQ-VLLQEVYQSPCTMG 287

  Fly   367 NRTWTY-GNVQYKVSGKENGKSSAEQPIVDFDACLELVKSKVMPLVKPKPFT------LKQHAVA 424
            .|...: |:....:||..|.           ..|.:|| |::.. :...||:      :.|..||
  Rat   288 QRPRAFNGSAIVSLSGTSNA-----------TLCRDLV-SRLFN-ISSCPFSQCSFNGVFQPPVA 339

  Fly   425 ----AFS--YY------------------FERAIE-----------SGLVDPLA--GGET----- 447
                |||  ||                  .|.|.|           |.|..|.:  .|.|
  Rat   340 GNFIAFSAFYYTVDFLTTVMGLPVGTLKQLEEATEITCNQTWTEWPSLLSSPSSCWKGRTQGSSS 404

  Fly   448 -----TVEAYRKKAQEICAIPNDEQPFMCFDLTFISTLLREGFGLNDG--KKIKLYKKIDGHEIS 505
                 .|...:.:..:.||:           ..||..||..|:..::.  :::...||.....:.
  Rat   405 HELQARVPGQKTRLADYCAV-----------AMFIHQLLSRGYHFDERSFREVVFQKKAADTAVG 458

  Fly   506 WALGCAYNV 514
            ||||...|:
  Rat   459 WALGYMLNL 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NTPase	NP_001259972.1	ASKHA_NBD_NTPDase5-like	142..515	CDD:466896	118/462 (26%)
Entpd2	XP_017447512.1	ASKHA_NBD_NTPDase2	37..472	CDD:466961	118/464 (25%)