DRSC/TRiP Functional Genomics Resources

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Protein Alignment Prx6a and MDS3

DIOPT Version :10

Sequence 1:NP_523463.2 Gene:Prx6a / 33493 FlyBaseID:FBgn0031479 Length:222 Species:Drosophila melanogaster
Sequence 2:NP_011318.2 Gene:MDS3 / 852678 SGDID:S000003165 Length:1487 Species:Saccharomyces cerevisiae


Alignment Length:214 Identity:43/214 - (20%)
Similarity:70/214 - (32%) Gaps:81/214 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 KALNI--------GDQF----------PNFTAETSEGRIDFYDWMQDSWAILFSHPADFTPVCTT 50
            |.||:        ||.|          ||:  ::|......||.....|                
Yeast   353 KLLNVPYELLAPTGDYFGFNIIIGGFHPNY--QSSNFHCFIYDINSGKW---------------- 399

  Fly    51 ELSRVAALIPEFQKRGVKPIALSCDTVESHKGW-----------------IED-----IKSFGKL 93
              ||||...|:            || :..|:.|                 .:|     ::.|..|
Yeast   400 --SRVATACPD------------CD-INKHRFWRVFVWKSHHQTILLGTKTDDYYSPSVQRFDHL 449

  Fly    94 SSFDYPIIADDKRELALKFNMLDKDEINAEGIPLTCRAVFVVDDKKKLRLSILYPATTGRNFDEI 158
            |:|..|::     .:..|...|...:|:|..:|:.........|....::|....||:  .|:..
Yeast   450 STFGLPLV-----NIFNKTIQLPHHKISASSLPIPIENFAKHKDTPLKKVSFTSSATS--QFENY 507

  Fly   159 LRVI-DSLQLTQTKSVATP 176
            :|.| ..|:::..:||..|
Yeast   508 IRYIAPPLEMSSIQSVFPP 526

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Prx6aNP_523463.2 PRX_1cys 8..220 CDD:239314 40/210 (19%)
MDS3NP_011318.2 NanM <156..>263 CDD:442289
KELCH repeat 160..210 CDD:276965
KELCH repeat 216..263 CDD:276965
Blue background indicates that the domain is not in the aligned region.

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