DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prx6005 and PRX1

DIOPT Version :9

Sequence 1:	NP_523463.2	Gene:	Prx6005 / 33493	FlyBaseID:	FBgn0031479	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_009489.1	Gene:	PRX1 / 852215	SGDID:	S000000160	Length:	261	Species:	Saccharomyces cerevisiae

Alignment Length:	217	Identity:	104/217 - (47%)
Similarity:	138/217 - (63%)	Gaps:	10/217 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LNIGDQFPNFTAETSEGRIDFYDWMQDSWAILFSHPADFTPVCTTELSRVAALIPEFQKRGVKPI 70
            |.|....|||.|:|:.|:|:|||::.|||.:|||||||||||||||:|..|.|.|||.||.||.|
Yeast    49 LRINSDAPNFDADTTVGKINFYDYLGDSWGVLFSHPADFTPVCTTEVSAFAKLKPEFDKRNVKLI 113

  Fly    71 ALSCDTVESHKGWIEDIKSFGKLSSFDYPIIADDKRELALKFNMLDKD---EINAEGIPLTCRAV 132
            .||.:.||||:.||:|||...|:.:..:|||.|..|.:|..::|:|.:   .|| :|...|.|:|
Yeast   114 GLSVEDVESHEKWIQDIKEIAKVKNVGFPIIGDTFRNVAFLYDMVDAEGFKNIN-DGSLKTVRSV 177

  Fly   133 FVVDDKKKLRLSILYPATTGRNFDEILRVIDSLQLTQTKSVATPADWKQGGKCMVLPTVKAEDVP 197
            ||:|.|||:||...||:|.|||..|:|||||:||||..:.|.||.:|:.....::.|:|..::..
Yeast   178 FVIDPKKKIRLIFTYPSTVGRNTSEVLRVIDALQLTDKEGVVTPINWQPADDVIIPPSVSNDEAK 242

  Fly   198 KLFPDGIETIELPSGKSYLRIT 219
            ..|....|.      |.|||.|
Yeast   243 AKFGQFNEI------KPYLRFT 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prx6005	NP_523463.2	PRX_1cys	8..220	CDD:239314	103/215 (48%)
Prx6005	NP_523463.2	AhpC	8..198	CDD:223527	96/192 (50%)
PRX1	NP_009489.1	PRX_1cys	51..259	CDD:239314	103/215 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	145	1.000	Domainoid score	I981
eggNOG	1	0.900	-	-		E1_COG0450
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3606
Inparanoid	1	1.050	198	1.000	Inparanoid score	I866
Isobase	1	0.950	-	0	Normalized mean entropy	S632
OMA	1	1.010	-	-		QHG60653
OrthoFinder	1	1.000	-	-		FOG0002615
OrthoInspector	1	1.000	-	-		otm46541
orthoMCL	1	0.900	-	-		OOG6_100111
Panther	1	1.100	-	-	O	PTHR43503
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2241
SonicParanoid	1	1.000	-	-		X1721
TreeFam	1	0.960	-	-
	15	14.810