DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prx6005 and Prdx6b

DIOPT Version :9

Sequence 1:	NP_523463.2	Gene:	Prx6005 / 33493	FlyBaseID:	FBgn0031479	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_796230.1	Gene:	Prdx6b / 320769	MGIID:	1336888	Length:	224	Species:	Mus musculus

Alignment Length:	220	Identity:	123/220 - (55%)
Similarity:	157/220 - (71%)	Gaps:	3/220 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LNIGDQFPNFTAETSEGRIDFYDWMQDSWAILFSHPADFTPVCTTELSRVAALIPEFQKRGVKPI 70
            |.:|::.|:|.|.|:.|||.|:|::.:||.:|||||.||||||||||.|.|.|.|||.||.||.|
Mouse     5 LLLGEEAPDFEANTTIGRIRFHDFLGNSWGMLFSHPKDFTPVCTTELGRAAKLAPEFAKRNVKLI 69

  Fly    71 ALSCDTVESHKGWIEDIKSFGKLS---SFDYPIIADDKRELALKFNMLDKDEINAEGIPLTCRAV 132
            |||.|:||.|..|.:||.::...:   ...:|||.|..|::::.|.|||..|.:|..:|||.|.|
Mouse    70 ALSVDSVEDHLAWSKDINAYNGATPKEKLPFPIIDDKDRDISILFCMLDPVEKDANSMPLTARGV 134

  Fly   133 FVVDDKKKLRLSILYPATTGRNFDEILRVIDSLQLTQTKSVATPADWKQGGKCMVLPTVKAEDVP 197
            |:....|||::|:|||.:||||||||||||||||||:||.||||.|||:|...||||.:..|:..
Mouse   135 FIFGPDKKLKMSLLYPNSTGRNFDEILRVIDSLQLTETKPVATPVDWKKGESVMVLPDLPEEEAK 199

  Fly   198 KLFPDGIETIELPSGKSYLRITPQP 222
            :.||.||.|.:|||||:|||.||||
Mouse   200 RCFPKGISTTKLPSGKNYLRYTPQP 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prx6005	NP_523463.2	PRX_1cys	8..220	CDD:239314	118/214 (55%)
Prx6005	NP_523463.2	AhpC	8..198	CDD:223527	105/192 (55%)
Prdx6b	NP_796230.1	AhpC	5..199	CDD:223527	106/193 (55%)
Prdx6b	NP_796230.1	PRX_1cys	7..222	CDD:239314	118/214 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	50	1.000	Domainoid score	I11609
eggNOG	1	0.900	-	-		E1_COG0450
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	256	1.000	Inparanoid score	I3147
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60653
OrthoDB	1	1.010	-	-		D1129256at2759
OrthoFinder	1	1.000	-	-		FOG0002615
OrthoInspector	1	1.000	-	-		otm43402
orthoMCL	1	0.900	-	-		OOG6_100111
Panther	1	1.100	-	-	O	PTHR43503
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1721
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840