DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prx6005 and Prdx1

DIOPT Version :9

Sequence 1:	NP_523463.2	Gene:	Prx6005 / 33493	FlyBaseID:	FBgn0031479	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_035164.1	Gene:	Prdx1 / 18477	MGIID:	99523	Length:	199	Species:	Mus musculus

Alignment Length:	203	Identity:	68/203 - (33%)
Similarity:	98/203 - (48%)	Gaps:	18/203 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSGKALNIGDQFPNF--TAETSEGR---IDFYDWMQDSWAILFSHPADFTPVCTTELSRVAALIP 60
            ||.....||...|||  ||...:|:   |...:: :..:.:.|.:|.|||.||.||:...:....
Mouse     1 MSSGNAKIGYPAPNFKATAVMPDGQFKDISLSEY-KGKYVVFFFYPLDFTFVCPTEIIAFSDRAD 64

  Fly    61 EFQKRGVKPIALSCDTVESHKGWIEDIKSFGKLSSFDYPIIADDKRELALKFNMLDKDEINAEGI 125
            ||:|...:.|..|.|:...|..||...|..|.|...:.|:|:|.||.:|..:.:|..|    |||
Mouse    65 EFKKLNCQVIGASVDSHFCHLAWINTPKKQGGLGPMNIPLISDPKRTIAQDYGVLKAD----EGI 125

  Fly   126 PLTCRAVFVVDDKKKLRLSILYPATTGRNFDEILRVIDSLQLTQTKSVATPADWKQGGKCMVLPT 190
              :.|.:|::|||..||...:.....||:.|||:|::.:.|.|.......||.||.|.     .|
Mouse   126 --SFRGLFIIDDKGILRQITINDLPVGRSVDEIIRLVQAFQFTDKHGEVCPAGWKPGS-----DT 183

  Fly   191 VKAEDVPK 198
            :| .||.|
Mouse   184 IK-PDVNK 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prx6005	NP_523463.2	PRX_1cys	8..220	CDD:239314	66/196 (34%)
Prx6005	NP_523463.2	AhpC	8..198	CDD:223527	65/194 (34%)
Prdx1	NP_035164.1	PRX_Typ2cys	8..180	CDD:239313	60/178 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0450
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100111
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.710