DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prx6005 and prdx-6

DIOPT Version :9

Sequence 1:	NP_523463.2	Gene:	Prx6005 / 33493	FlyBaseID:	FBgn0031479	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_741287.1	Gene:	prdx-6 / 176837	WormBaseID:	WBGene00021401	Length:	231	Species:	Caenorhabditis elegans

Alignment Length:	222	Identity:	102/222 - (45%)
Similarity:	142/222 - (63%)	Gaps:	9/222 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LNIGDQFPNFTAETS-EGRIDFYDWMQDSWAILFSHPADFTPVCTTELSRVAALIPEFQKRGVKP 69
            :.:||..||||.||. ......::::.:.|.:||||||||||||||||:.:..|.|||:||.|:.
Worm     1 MKLGDTVPNFTFETDLRKNQTLHNYIGEQWLMLFSHPADFTPVCTTELAELVKLAPEFRKRHVQI 65

  Fly    70 IALSCDTVESHKGWIEDIKSFGKLSS----FDYPIIADDKRELALKFNMLDKDEINAEGIPLTCR 130
            :|:|.|:.|:|:.|.:||.|..:||:    ..:.||||..|.:..:..|:|.||:|:|||.|:.|
Worm    66 LAISIDSSETHRDWAKDINSVAQLSNCGSHLPFEIIADTDRSICTELGMIDPDEMNSEGICLSAR 130

  Fly   131 AVFVVDDKKKLRLSILYPATTGRNFDEILRVIDSLQLTQTKSVATPADWKQGGKCMVLPTVKAED 195
            ||.:....|||:..||||||.||||.||||::|.:||.....|||||:|..|...:..|::..|.
Worm   131 AVMLFGPDKKLKSKILYPATFGRNFVEILRMVDGVQLGTKAPVATPANWIAGDNVIAQPSLSQER 195

  Fly   196 VPKLF----PDGIETIELPSGKSYLRI 218
            |.:..    ||..:|:.|||||||||:
Worm   196 VIQELCGGDPDKCKTVPLPSGKSYLRV 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prx6005	NP_523463.2	PRX_1cys	8..220	CDD:239314	102/220 (46%)
Prx6005	NP_523463.2	AhpC	8..198	CDD:223527	90/194 (46%)
prdx-6	NP_741287.1	PRX_1cys	3..221	CDD:239314	100/217 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158548
Domainoid	1	1.000	124	1.000	Domainoid score	I3407
eggNOG	1	0.900	-	-		E1_COG0450
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3606
Inparanoid	1	1.050	194	1.000	Inparanoid score	I2532
Isobase	1	0.950	-	0	Normalized mean entropy	S632
OMA	1	1.010	-	-		QHG60653
OrthoDB	1	1.010	-	-		D1129256at2759
OrthoFinder	1	1.000	-	-		FOG0002615
OrthoInspector	1	1.000	-	-		otm14762
orthoMCL	1	0.900	-	-		OOG6_100111
Panther	1	1.100	-	-	LDO	PTHR43503
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2241
SonicParanoid	1	1.000	-	-		X1721
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	16	15.790