DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8814 and ACBD4

DIOPT Version :9

Sequence 1:	NP_608729.1	Gene:	CG8814 / 33492	FlyBaseID:	FBgn0031478	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	XP_016880573.1	Gene:	ACBD4 / 79777	HGNCID:	23337	Length:	348	Species:	Homo sapiens

Alignment Length:	219	Identity:	63/219 - (28%)
Similarity:	100/219 - (45%)	Gaps:	61/219 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EERFQAAVNVIKGLPKNGPYQPSTSMMLKFYGLFKQATEGRPDVDKKPGFWDIVGKAKWQAWNDN 69
            :::|||||:||:.|||||.|:||...||:||..:||||.| |.:..:|||||.:|:.||.|||..
Human    13 QKQFQAAVSVIQNLPKNGSYRPSYEEMLRFYSYYKQATMG-PCLVPRPGFWDPIGRYKWDAWNSL 76

  Fly    70 RHLTKEEAMQRYVESL----QEIIETMSFTENVQNFVGSLDSLGNISLD---------------E 115
            ..:::||||..|:..:    |::|:|:...|..::..|..:.|..:..|               :
Human    77 GKMSREEAMSAYITEMKLVAQKVIDTVPLGEVAEDMFGYFEPLYQVIPDMPRPPETFLRRVTGWK 141

  Fly   116 LELVSPGMKELAE----------------------SHPNSPFHSRTNSPQH--------GSSC-- 148
            .::|:..:..::|                      :.|.||.|..|.:|:.        ..||
Human   142 EQVVNGDVGAVSEPPCLPKEPAPPSPASLWAVTLPTPPQSPIHPGTWTPRFSVIPWSSWSLSCSL 206

  Fly   149 ---------NGEPEPEPQATSTAP 163
                     :|:...|.....|||
Human   207 THLSRFGQSSGQHLEESVIPGTAP 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8814	NP_608729.1	ACBP	5..90	CDD:279259	42/88 (48%)
CG8814	NP_608729.1	DUF1664	<217..272	CDD:285172
ACBD4	XP_016880573.1	ACBP	13..93	CDD:376410	41/80 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155547
Domainoid	1	1.000	102	1.000	Domainoid score	I6845
eggNOG	1	0.900	-	-		E1_COG4281
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1546859at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm40853
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23310
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1702
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.810