DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8814 and Acbd5

DIOPT Version :9

Sequence 1:	NP_608729.1	Gene:	CG8814 / 33492	FlyBaseID:	FBgn0031478	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	XP_017456071.1	Gene:	Acbd5 / 307170	RGDID:	1309411	Length:	531	Species:	Rattus norvegicus

Alignment Length:	506	Identity:	119/506 - (23%)
Similarity:	172/506 - (33%)	Gaps:	208/506 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EERFQAAVNVIKGLPKNGPYQPSTSMMLKFYGLFKQATEGRPDVDKKPGFWDIVGKAKWQAWNDN 69
            |.||:|||.||:.|||||.:||:..|||:||..:|||||| |....:|||||.:|:.||.||:..
  Rat    45 ETRFEAAVKVIQSLPKNGSFQPTNEMMLRFYSFYKQATEG-PCKLSRPGFWDPIGRYKWDAWSSL 108

  Fly    70 RHLTKEEAMQRYVESLQEIIETMSFTENVQNFVGSLDSLGNISLDELELVSPGMKELAESHPNSP 134
            ..:||||||..|||.:::|||||..||.|:..              |.::.| ..|:.|...||.
  Rat   109 GDMTKEEAMIAYVEEMKKIIETMPMTEKVEEL--------------LHVIGP-FYEIVEDKKNSK 158

  Fly   135 FHSRTN-----------------SPQHGSSCNGEPEPEPQATSTAPLATSETIK---ENGHSSPP 179
            ....|:                 :..:..:.||:.|.......:......|.:|   ::|.....
  Rat   159 SSDLTSVRLEKISKYLEDLGNVLTSSNAKAVNGKAESSDSGAESEEEEAQEELKGAEQSGSDDKK 223

  Fly   180 L-------------TNGY----------------------GPKPTASYTQ----------HDT-- 197
            :             ||||                      ..|||...:|          .||
  Rat   224 MMTKSTDKNLEIIVTNGYKDSFAQDSDIHTDSSRSARRSEDKKPTDQSSQQTGNTVLCVHQDTNE 288

  Fly   198 ---------HNFTSNSSVAIVDPSDDEY---------------------DDP------------- 219
                     |:.||:|...:...|.:::                     .||
  Rat   289 DPGEDASGVHHLTSDSDSEVYCDSMEQFGQEESLDSFMSNNGHFQYYLGGDPAQHLEGSGFCEDA 353

  Fly   220 ----------------------------------------------YDLS--------HELT--- 227
                                                          .|:|        |.:.
  Rat   354 QLSPGNGSIGKMQMRAVKGKGEVKHGGEDGRSSSGTPHREKRGGESEDISGVRRGRVGHRMPHLS 418

  Fly   228 -----QAIGQNTD-------------LLRQIQAAITRMNSDVGAVQQRVRSLEQSLNELRSGQ-K 273
                 :.:|...|             |..||...:.|:..|:..|.||:..||    .|.:.| |
  Rat   419 EGTKGRQVGSGGDGERWGSDRGSRGSLNEQIALVLIRLQEDMQNVLQRLHKLE----TLTASQAK 479

  Fly   274 AAKGTVAQPRS-LPAWWPFRNISPLWFAVLILWPFLVRRFARMLQSNPQRR 323
            .:..|..||.| .|:|||| .:||...|..|:|||:.:....:.....:|:
  Rat   480 LSWQTSNQPSSQRPSWWPF-EMSPGALAFAIIWPFIAQWLVHLYYQRRRRK 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8814	NP_608729.1	ACBP	5..90	CDD:279259	47/84 (56%)
CG8814	NP_608729.1	DUF1664	<217..272	CDD:285172	18/142 (13%)
Acbd5	XP_017456071.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349433
Domainoid	1	1.000	101	1.000	Domainoid score	I6759
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	159	1.000	Inparanoid score	I4161
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1546859at2759
OrthoFinder	1	1.000	-	-		FOG0004024
OrthoInspector	1	1.000	-	-		otm44994
orthoMCL	1	0.900	-	-		OOG6_103494
Panther	1	1.100	-	-	LDO	PTHR23310
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1702
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.900