DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8814 and Eci2

DIOPT Version :9

Sequence 1:	NP_608729.1	Gene:	CG8814 / 33492	FlyBaseID:	FBgn0031478	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001103801.1	Gene:	Eci2 / 23986	MGIID:	1346064	Length:	391	Species:	Mus musculus

Alignment Length:	131	Identity:	46/131 - (35%)
Similarity:	63/131 - (48%)	Gaps:	8/131 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAAIEERFQAAVNVIKGLPKNGPYQPSTSMMLKFYGLFKQATEGRPDVDKKPGFWDIVGKAKWQA 65
            |.|.::.|:.|:|.:|.|.|:    |...:.|:.|.|:|||||| |....|||..|.|.||||.|
Mouse    34 MRASQQDFENALNQVKLLKKD----PGNEVKLRLYALYKQATEG-PCNMPKPGMLDFVNKAKWDA 93

  Fly    66 WNDNRHLTKEEAMQRYVESLQEIIETMSFTENVQNFVGSLDSLGNISLDELELVSPGMKELAESH 130
            ||....|.||.|.|.||:.:..:   .|.:|.........|.....|.|.|.....|:.::..:.
Mouse    94 WNALGSLPKETARQNYVDLVSSL---SSSSEAPSQGKRGADEKARESKDILVTSEDGITKITFNR 155

  Fly   131 P 131
            |
Mouse   156 P 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8814	NP_608729.1	ACBP	5..90	CDD:279259	36/84 (43%)
CG8814	NP_608729.1	DUF1664	<217..272	CDD:285172
Eci2	NP_001103801.1	ACBP	38..113	CDD:279259	36/79 (46%)
		Acyl-CoA binding. /evidence=ECO:0000250	64..68		2/3 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	116..136		3/22 (14%)
		crotonase-like	139..389	CDD:304874	4/18 (22%)
		ECH-like	149..319		1/8 (13%)
		Substrate binding. /evidence=ECO:0000250\|UniProtKB:Q05871	196..200
		Microbody targeting signal. /evidence=ECO:0000255	389..391
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4281
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810