DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31694 and ifrd1

DIOPT Version :9

Sequence 1:	NP_722858.1	Gene:	CG31694 / 33489	FlyBaseID:	FBgn0051694	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_001070023.1	Gene:	ifrd1 / 555178	ZFINID:	ZDB-GENE-030131-6132	Length:	427	Species:	Danio rerio

Alignment Length:	433	Identity:	164/433 - (37%)
Similarity:	245/433 - (56%)	Gaps:	25/433 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPRRNKKSAAG--RGRTNDSNSEDESFDNVSVYSHMSE--VASSEA--TDELANERFEEKFEKAL 59
            |||..|:|..|  :|.....:.||.|.:.:|..|.:||  .|:.||  |:|:|.|.|:.|.:..:
Zfish     1 MPRAKKRSGKGGQQGNVQPFSDEDASIETLSHCSSLSERTSAAEEAGETEEMAEEDFQYKLKVYI 65

  Fly    60 EQATEKSAQTRVQALQAICELLMHRYMPDFVEDRKMTLMDFVEKSIRRGKGQEQVWGARLAPLLV 124
            :...:|||:||..||..:...:..:.:.||:.:|:||:.|.:|:.:::|||.||...|.||.||.
Zfish    66 DSTVDKSAKTRQGALDGLKTAMATKILYDFISERRMTITDGIERCLKKGKGVEQSAAASLACLLC 130

  Fly   125 LQMGG---DEGISKAMNQFLLNTVQDKSVGFDARAKCCTAVGLLSFLGCEDVGELVHLMQSFEAI 186
            :|:|.   .|.:.|::.......:.|.:....||..|.|::||.:.:..:|:.::...|:.||::
Zfish   131 IQLGSGIESEEVFKSLKPVFKTILNDGTANIQARQACATSLGLCTLVAEDDIMDVYATMECFESL 195

  Fly   187 FAGSYLRGDDKTPVSVTAEAGTFHAEALNAWGLLLTLIPSGDFVSLMTTGQNMFPSIKKFLG--- 248
            |..||:|.|...| ||:......|..||.:|.||||:          .||.::....:|.|.
Zfish   196 FTRSYIREDGSRP-SVSPPVTQLHTNALLSWALLLTI----------CTGSHIRAIAQKHLAKLP 249

  Fly   249 -LLQSTHLDVRMAAGETIALILESGRAHEEDFLEDDIAELSEAVKQLATDSHKYRAKRDRKAQRA 312
             ||::..:::|:||||||||:.|..|..|.:|..|:...|.|.:..||||.:|:|||.|::.||:
Zfish   250 RLLENDDVNMRIAAGETIALLFELIRDVEPEFDLDEWEPLCEKLNALATDCNKHRAKTDKRKQRS 314

  Fly   313 TFRDVLRYLEEDISPEISIRFGTESLTLDSWSIHHQYSAMCTVMGPGMTSQLQENEFIRDIFQLG 377
            .|||||:.:|:......:||||||.:.:|||.....|.|....:|.||...||.||||||:|:||
Zfish   315 VFRDVLKAVEDGDFQSETIRFGTERMLIDSWVRKRTYDAFREFVGSGMNYHLQANEFIRDVFELG 379

  Fly   378 PRPTNTGINGNAKVKPTKLERHLVNAAAFKARSITRGKNRDKR 420
            | |..........:|.::|||||.||||||||:..|.|.||||
Zfish   380 P-PMLIDSATLKAMKSSRLERHLYNAAAFKARTKARNKCRDKR 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31694	NP_722858.1	IFRD	21..321	CDD:282813	109/310 (35%)
CG31694	NP_722858.1	IFRD_C	367..421	CDD:282665	31/54 (57%)
ifrd1	NP_001070023.1	IFRD	21..323	CDD:282813	109/312 (35%)
ifrd1	NP_001070023.1	IFRD_C	369..421	CDD:282665	29/52 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595850
Domainoid	1	1.000	174	1.000	Domainoid score	I3622
eggNOG	1	0.900	-	-		E1_KOG2842
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31043
Inparanoid	1	1.050	262	1.000	Inparanoid score	I3087
OMA	1	1.010	-	-		QHG59129
OrthoDB	1	1.010	-	-		D1153292at2759
OrthoFinder	1	1.000	-	-		FOG0002385
OrthoInspector	1	1.000	-	-		otm26501
orthoMCL	1	0.900	-	-		OOG6_103218
Panther	1	1.100	-	-	O	PTHR12354
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3832
SonicParanoid	1	1.000	-	-		X2973
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800