DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31694 and ifrd1

DIOPT Version :9

Sequence 1:	NP_722858.1	Gene:	CG31694 / 33489	FlyBaseID:	FBgn0051694	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_001016124.1	Gene:	ifrd1 / 548878	XenbaseID:	XB-GENE-489784	Length:	427	Species:	Xenopus tropicalis

Alignment Length:	450	Identity:	161/450 - (35%)
Similarity:	237/450 - (52%)	Gaps:	60/450 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPRRNKKS--AAGRGRTNDS--NSEDESFDNVSVYSHMSEVAS------SEATDELANERFEEKF 55
            ||:..|:|  |||....|..  :.:|.|.:.:|..|..|:|||      :|..:..|.|.||.|.
Frog     1 MPKPKKRSNRAAGGQHKNVQAFSDDDSSIETMSHCSSFSDVASFAEDAGTEVDEYAAQEDFEYKL 65

  Fly    56 EKALEQATEKSAQTRVQALQAICELLMHRYMPDFVEDRKMTLMDFVEKSIRRGKGQEQVWGARLA 120
            ...::...:|||:||..||:.:...|..:.:.||:.:|:|||.|.:|:.:::||.:||...|.||
Frog    66 RGLIDLTMDKSAKTRQAALEGLKTGLSSKLLYDFIMERRMTLTDSIERCLKKGKSEEQQVAAALA 130

  Fly   121 PLLVLQMGG---DEGISKAMNQFLLNTVQDKSVGFDARAKCCTAVGLLSFLGCEDVGELVHLMQS 182
            .||..|:|.   .|.:.:.:...|.:.|.|:|....||..|.|.:||..|:..:|:.:|...|:.
Frog   131 CLLCCQLGSGIESEEVFRTIAPVLKSIVCDRSASTQARQACATYLGLCCFVATDDIEDLYTTMEC 195

  Fly   183 FEAIFAGSYLRGDDKTPVSVTAEAG-----TFHAEALNAWGLLLTLIPSGDFVSLMTTGQNMFPS 242
            .|.:|...|           .:|:|     ..|.:||.:|.||||:..:.:
Frog   196 MENLFTKQY-----------HSESGADNCSALHIQALQSWALLLTICHNSE-------------- 235

  Fly   243 IKKFLG--------LLQSTHLDVRMAAGETIALILESGRAHEEDFLEDDIAELSEAVKQLATDSH 299
            :||.|.        ||....:::|:|||||:||:.|..|..:.||..:|:..|::.:|.||||.:
Frog   236 VKKKLDIHLPKLPRLLSCGDVNMRIAAGETLALLFELAREADADFYFEDLEPLTQTLKSLATDCN 300

  Fly   300 KYRAKRDRKAQRATFRDVLRYLEE-DISPEISIRFGTESLTLDSWSIHHQYSAMCTVMGPGMTSQ 363
            |:|||.||:.||:.|||||:.:|| |..|| :||||.|.:.:|||.....|.....:.|.||...
Frog   301 KHRAKIDRRKQRSVFRDVLKAIEEGDFQPE-TIRFGRERMHIDSWVKRLTYGTFKELFGSGMQYH 364

  Fly   364 LQENEFIRDIFQLGPRPTNTGINGNAKVKPTKL---ERHLVNAAAFKARSITRGKNRDKR 420
            |..|.|:|.||:||| |.   :...|.:|..|:   ||||.|:||||||:..|.|.||||
Frog   365 LLTNVFLRSIFELGP-PM---LLDTATIKAMKVSREERHLNNSAAFKARTKARSKLRDKR 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31694	NP_722858.1	IFRD	21..321	CDD:282813	106/321 (33%)
CG31694	NP_722858.1	IFRD_C	367..421	CDD:282665	28/56 (50%)
ifrd1	NP_001016124.1	IFRD	23..322	CDD:368234	106/323 (33%)
ifrd1	NP_001016124.1	IFRD_C	368..421	CDD:368148	28/56 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	165	1.000	Domainoid score	I3857
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H31043
Inparanoid	1	1.050	231	1.000	Inparanoid score	I3358
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1153292at2759
OrthoFinder	1	1.000	-	-		FOG0002385
OrthoInspector	1	1.000	-	-		otm48660
Panther	1	1.100	-	-	O	PTHR12354
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3832
SonicParanoid	1	1.000	-	-		X2973
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.190