DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31694 and F58B3.6

DIOPT Version :9

Sequence 1:	NP_722858.1	Gene:	CG31694 / 33489	FlyBaseID:	FBgn0051694	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_502197.2	Gene:	F58B3.6 / 178090	WormBaseID:	WBGene00010232	Length:	410	Species:	Caenorhabditis elegans

Alignment Length:	444	Identity:	129/444 - (29%)
Similarity:	221/444 - (49%)	Gaps:	63/444 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RNKK-------SAAGRGRTNDSNSED-ESFDNVSVYSHMSEVASSEATDELANERFEEKFEKALE 60
            |||.       ..|..|| |||:|:| ||    |.|::..::.|.....|..|:.:::..:. |:
Worm     5 RNKNKDKDPYIGPAKTGR-NDSDSDDSES----SAYTYNEDIQSIMGDVEDMNDVYDQLVDN-LD 63

  Fly    61 QATEKSAQTRVQALQAICELLMHRYMPDFVEDRKMTLMDFVEKSIRRGKGQEQVWGARLAPLLVL 125
            :|.:|::.||:..|..:...|..:..|:|:...|.|:|....:...:...:.| :.|||..|:.:
Worm    64 RAQDKNSTTRIDGLHRVNLALTAKPAPEFINRNKETIMAVCSRMANKPDSEAQ-FLARLVGLVAV 127

  Fly   126 QMGGD--EGISKAMNQFLLNTVQDKSVGFDARAKCCTAVGLLSFLGCEDVGELVHLMQSFEAIFA 188
            |.|.:  |.|::.|:| :...:.|.|.....|..|.|::.:::.:.|.:..|:....::..  ||
Worm   128 QAGEEISEMIAEPMSQ-MRTILMDASRCVFLRTACATSLAIVTRIACSEDEEVTANAKACR--FA 189

  Fly   189 GSYLRGDDKTPVSVTA-EAGTFHAE----ALNAWGLLLTLIPSGDFVSLMTTGQNMFPSIKKFLG 248
            .::      |.||.:| :.|  ||:    :|.:|.::|.   ..||.::    .:......|.:.
Worm   190 WAH------TKVSGSANDIG--HAKLVGTSLFSWCVMLL---DADFQTI----NDAVADQPKIVT 239

  Fly   249 LLQSTHLDVRMAAGETIALILESGRAHEEDFLED--------DIAELSEAVKQLATDSHKYRAKR 305
            ||.|..|:||:||.||:|.:      ||  |::|        :...:...:.|:..||.|.:.|:
Worm   240 LLSSNQLEVRLAAAETLAFL------HE--FMQDARPGFRFPNKEHVLSLLDQMVNDSSKKKTKK 296

  Fly   306 DRKAQRATFRDVLRYL-EEDISPEISIRFGTESLTLDSWSIHHQYSAMCTVMGPGMTSQLQENEF 369
            |::|||...||:..:: :||.:||::::.|.::|:|||.:|...|...|.::..|:..||..||.
Worm   297 DKRAQRYAVRDIRAFIADEDDAPEVNVKIGQQTLSLDSCAIKIFYDTTCDLLHGGLAQQLLHNEV 361

  Fly   370 IRDIFQLGPRPTNTGINGNAKVKPTKLERHLVNAAAFKARSITRGKNRDKRSAV 423
            :||:|.|||.......:.|      |..|..|:.||.|.|:..|||.|||||.|
Worm   362 LRDVFDLGPIALEPAESAN------KQSRLAVHEAADKHRNQVRGKQRDKRSTV 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31694	NP_722858.1	IFRD	21..321	CDD:282813	79/315 (25%)
CG31694	NP_722858.1	IFRD_C	367..421	CDD:282665	22/53 (42%)
F58B3.6	NP_502197.2	IFRD	47..312	CDD:282813	73/292 (25%)
F58B3.6	NP_502197.2	IFRD_C	359..407	CDD:282665	22/53 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167182
Domainoid	1	1.000	79	1.000	Domainoid score	I5625
eggNOG	1	0.900	-	-		E1_KOG2842
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31043
Inparanoid	1	1.050	148	1.000	Inparanoid score	I2988
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59129
OrthoDB	1	1.010	-	-		D1153292at2759
OrthoFinder	1	1.000	-	-		FOG0002385
OrthoInspector	1	1.000	-	-		oto19995
orthoMCL	1	0.900	-	-		OOG6_103218
Panther	1	1.100	-	-	LDO	PTHR12354
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3832
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.840