DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31694 and Ifrd1

DIOPT Version :9

Sequence 1:	NP_722858.1	Gene:	CG31694 / 33489	FlyBaseID:	FBgn0051694	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_038590.2	Gene:	Ifrd1 / 15982	MGIID:	1316717	Length:	449	Species:	Mus musculus

Alignment Length:	453	Identity:	159/453 - (35%)
Similarity:	240/453 - (52%)	Gaps:	38/453 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPRRNKKSAAGRG--------------------RT----NDSNSEDESFDNVSVYSHMSEVASS- 40
            ||:..|::|..||                    ||    :|.::..|:..:.|.||..|..|..
Mouse     1 MPKNKKRNAPHRGGGGGGGSGAATSAATAGGPHRTVQPFSDEDASIETMSHCSGYSDPSSFAEDG 65

  Fly    41 -EATDEL-ANERFEEKFEKALEQATEKSAQTRVQALQAICELLMHRYMPDFVEDRKMTLMDFVEK 103
             |..||. ..|..|.|.:..::...:|||:||..||:.:...|..:.:.:||.:|:|||.|.:|:
Mouse    66 PEVLDEEGTQEDLEYKLKGLIDLTLDKSAKTRQAALEGLKNALSSKVLYEFVLERRMTLTDSIER 130

  Fly   104 SIRRGKGQEQVWGARLAPLLVLQMG---GDEGISKAMNQFLLNTVQDKSVGFDARAKCCTAVGLL 165
            .:::||..||...|.:|.:|.:|:|   ..|.|.|.:...|...:.|.:....||..|.|..|:.
Mouse   131 CLKKGKSDEQRAAAAVASVLCIQLGPGFESEEILKTLGPILKKIICDGAASIQARQTCATCFGVC 195

  Fly   166 SFLGCEDVGELVHLMQSFEAIFAGSYLRGDDKTPVSVTAEAGTFHAEALNAWGLLLTLIPSGDFV 230
            .|:..:|:.||...::.||.||..|||:..| |.|:.:......|..:|.||.||||:.|..:..
Mouse   196 CFIATDDITELYSTLECFENIFTKSYLKEKD-TNVTCSTPNTVLHISSLLAWTLLLTICPINEVK 259

  Fly   231 SLMTTGQNMFPSIKKFLGLLQSTHLDVRMAAGETIALILESGRAHEEDFLEDDIAELSEAVKQLA 295
            ..:....:..||      ||....:::|:||||::||:.|..|..|.||..:|:..|::.::.||
Mouse   260 KKLELHFHKLPS------LLSCDDVNMRIAAGESLALLFELARGMESDFFYEDMDSLTQMLRALA 318

  Fly   296 TDSHKYRAKRDRKAQRATFRDVLRYLEEDISPEISIRFGTESLTLDSWSIHHQYSAMCTVMGPGM 360
            ||.:|:|||.|::.||:.||||||.:||...|..:::||.|.:.:|||...|.|.....|:|.||
Mouse   319 TDGNKHRAKVDKRKQRSVFRDVLRAVEERDFPTETVKFGPERMYIDSWVKKHTYDTFKEVLGSGM 383

  Fly   361 TSQLQENEFIRDIFQLGPRPTNTGINGNAKVKPTKLERHLVNAAAFKARSITRGKNRDKRSAV 423
            ...||.|||:|::|:||| |..........:|.::.||||.|:||||||:..|.|.||||:.|
Mouse   384 QYHLQTNEFLRNVFELGP-PVMLDAATLKTMKISRFERHLYNSAAFKARTKARSKCRDKRADV 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31694	NP_722858.1	IFRD	21..321	CDD:282813	105/305 (34%)
CG31694	NP_722858.1	IFRD_C	367..421	CDD:282665	26/53 (49%)
Ifrd1	NP_038590.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..42		8/40 (20%)
		IFRD	40..344	CDD:282813	106/310 (34%)
		IFRD_C	390..443	CDD:282665	26/53 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850013
Domainoid	1	1.000	169	1.000	Domainoid score	I3800
eggNOG	1	0.900	-	-		E1_KOG2842
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31043
Inparanoid	1	1.050	250	1.000	Inparanoid score	I3210
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59129
OrthoDB	1	1.010	-	-		D1153292at2759
OrthoFinder	1	1.000	-	-		FOG0002385
OrthoInspector	1	1.000	-	-		otm43503
orthoMCL	1	0.900	-	-		OOG6_103218
Panther	1	1.100	-	-	O	PTHR12354
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3832
SonicParanoid	1	1.000	-	-		X2973
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.800