DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31694 and AgaP_AGAP012224

DIOPT Version :9

Sequence 1:	NP_722858.1	Gene:	CG31694 / 33489	FlyBaseID:	FBgn0051694	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	XP_320315.3	Gene:	AgaP_AGAP012224 / 1280469	VectorBaseID:	AGAP012224	Length:	382	Species:	Anopheles gambiae

Alignment Length:	395	Identity:	137/395 - (34%)
Similarity:	220/395 - (55%)	Gaps:	24/395 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 SHMSEVASSEATDELANERFEEKFEKALEQATEKSAQTRVQALQAICELLMHRYMPDFVEDRKMT 96
            |..:..|...:.||......|::..:|:|..:.:..||||.|.:::||.|:.||.|..:..|||.
Mosquito     1 SQAASPADCPSEDEAGEAVCEKELHQAIENTSFRRQQTRVSAYRSVCEGLVQRYCPGSLAGRKMA 65

  Fly    97 LMDFVEKSIRRGKGQEQVWGARLAPLLVLQMGGDEGISKAMNQF---LLNTVQDKSVG-FDARAK 157
            |::.|::|:|:|..:|::|...:.|||.||......:.:.:..|   ::..:.|.|:| .:.|.|
Mosquito    66 LVESVKRSLRKGNEEERLWAVSVIPLLALQSETCADVLELVETFKPVMIGILTDVSLGNSNVRMK 130

  Fly   158 CCTAVGLLSFLGCED--VGELVHLMQSFEAIFAGSYLRGDDKTPVSVTAEAGTFHAEALNAWGLL 220
            ||:.:|:|.|:| ||  ..|:|.||:..:......        ||.|   :|...|..|.:|.||
Mosquito   131 CCSVLGMLCFIG-EDERADEIVSLMKILQETIKNE--------PVLV---SGDIQAVELRSWTLL 183

  Fly   221 LTLIPSGDFVSLMTTGQNMFPSIKKFLGLLQSTHLDVRMAAGETIALILESGRAHEEDFLEDDIA 285
            |||:.....:....:...:.|  :..:.:|.|.||:||.|:|||:||:.|....|:..|.::|:.
Mosquito   184 LTLLSPQKILEHAKSANLLSP--RDLMAMLDSNHLEVRTASGETLALMHELLCQHDSSFFQEDLP 246

  Fly   286 ELSEAVKQLATDSHKYRAKRDRKAQRATFRDVLRYLEEDISPEISIRFGTESLTLDSWSIHHQYS 350
            :|...|::|:||::.::.||.||.||.||||||.||:|.:.||:.|:||.|:|.|:||.:|.:|.
Mosquito   247 DLLNTVRKLSTDAYHFQGKRGRKLQRITFRDVLLYLQEGVVPEMRIKFGDETLLLNSWMMHRRYD 311

  Fly   351 AMCTVMGPGMTSQLQENEFIRDIFQLGPRPTNTGINGNAKVKPTKLERHLVNAAAFKARSITRGK 415
            .:..|:|..:...|:||..:||:.:|||:..........::  .|..||..:|:  |.|||.|||
Mosquito   312 CLKDVLGMALNVHLEENALVRDLLKLGPKVERIVRRPGGRI--GKEFRHSFDAS--KERSIARGK 372

  Fly   416 NRDKR 420
            .||||
Mosquito   373 ERDKR 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31694	NP_722858.1	IFRD	21..321	CDD:282813	97/294 (33%)
CG31694	NP_722858.1	IFRD_C	367..421	CDD:282665	21/54 (39%)
AgaP_AGAP012224	XP_320315.3	IFRD	12..282	CDD:282813	95/283 (34%)
AgaP_AGAP012224	XP_320315.3	IFRD_C	328..377	CDD:282665	19/52 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2842
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59129
OrthoDB	1	1.010	-	-		D1153292at2759
OrthoFinder	1	1.000	-	-		FOG0002385
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12354
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.890