DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31694 and ifrd2

DIOPT Version :9

Sequence 1:	NP_722858.1	Gene:	CG31694 / 33489	FlyBaseID:	FBgn0051694	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	XP_031756986.1	Gene:	ifrd2 / 100380082	XenbaseID:	XB-GENE-1003246	Length:	454	Species:	Xenopus tropicalis

Alignment Length:	439	Identity:	154/439 - (35%)
Similarity:	238/439 - (54%)	Gaps:	34/439 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RRNKKSAAGRGRTNDSN-SEDESFDNVSVYSHMSEVAS--SEATDELANE-----RFEEKFEKA- 58
            |.|:...:..|...||. ||||:..:  |.||.|..:.  |.|.:...||     :.|::.:|.
Frog    33 RLNQLKGSRNGTRGDSEASEDEAASD--VLSHCSSASETVSVAEEGTGNEVDYQAQLEQRLDKLK 95

  Fly    59 --LEQATEKSAQTRVQALQAICELLMHRYMPDFVEDRKMTLMDFVEKSIRRGKGQEQVWGARLAP 121
              :|...:||.:||:.||..:...|..:.:.||:.:|::||.:.:|:.:::||.:||...|.:..
Frog    96 EDIENVMDKSVKTRLAALGNLRLALSSQVLADFLVERRITLAEALERCLKKGKEEEQTVAAIVLS 160

  Fly   122 LLVLQMG-GDEG--ISKAMNQFLLNTVQDKSVGFDARAKCCTAVGLLSFLGCEDVGELVHLMQSF 183
            ||.:|:| |.||  :.:.:...|.|.|.|.|.|..||..|.|.:||..::..|||.:|:..:...
Frog   161 LLCIQLGCGAEGEELFRCVKPVLTNLVTDSSAGLSARQSCATCLGLCCYIAAEDVEDLISTVCCL 225

  Fly   184 EAIFAGSYLRGDDKTPVSVTAEAGTFHAEALNAWGLLLTLIPSGDFVSLMTTGQNMFPSIKKFLG 248
            |.||...|......:|    |..|.... |:.:|.||||:.|:.....::.:.....|      |
Frog   226 EGIFTSCYSNCSAPSP----ALQGLLCC-AMQSWALLLTICPASHVHKVLESHLPRLP------G 279

  Fly   249 LLQSTHLDVRMAAGETIALILESGRAHEEDFLEDDIAELSEAVKQLATDSHKYRAKRDRKAQRAT 313
            :|....:.:|:|:||.:||:.|.|...:|||..:|...|...:|.|||||:|||||.||:.||:.
Frog   280 ILSCESVSLRIASGENLALLHELGHDLDEDFFYEDTDSLCVTLKALATDSNKYRAKTDRRKQRSI 344

  Fly   314 FRDVLRYLEEDISPEISIRFGTESLTLDSWSIHHQYSAMCTVMGPGMTSQLQENEFIRDIFQLGP 378
            |||||.|:|.....|.:|:||.|.:.:|||:....|:|...::|.|:...||.||.:|:||.|||
Frog   345 FRDVLHYIENGEFQEETIKFGLEVMFMDSWARRRTYNAFKEILGSGIRHHLQYNEVLREIFSLGP 409

  Fly   379 RPTNTGINGNAKVKPTKL---ERHLVNAAAFKARSITRGKNRDKRSAVV 424
             |.   :...|.:|.:|:   |:|:.|:||||||:..|.:.||||:.|:
Frog   410 -PL---VLDAATIKASKISRVEKHMFNSAAFKARTKARNRVRDKRADVL 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31694	NP_722858.1	IFRD	21..321	CDD:282813	105/312 (34%)
CG31694	NP_722858.1	IFRD_C	367..421	CDD:282665	25/56 (45%)
ifrd2	XP_031756986.1	IFRD	51..353	CDD:398602	107/314 (34%)
ifrd2	XP_031756986.1	IFRD_C	398..451	CDD:398486	25/56 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	165	1.000	Domainoid score	I3857
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	231	1.000	Inparanoid score	I3358
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1153292at2759
OrthoFinder	1	1.000	-	-		FOG0002385
OrthoInspector	1	1.000	-	-		otm48660
Panther	1	1.100	-	-	LDO	PTHR12354
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3832
SonicParanoid	1	1.000	-	-		X2973
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.190