DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2991 and march2

DIOPT Version :9

Sequence 1:	NP_608725.1	Gene:	CG2991 / 33488	FlyBaseID:	FBgn0031474	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_001038255.2	Gene:	march2 / 555611	ZFINID:	ZDB-GENE-050208-777	Length:	249	Species:	Danio rerio

Alignment Length:	189	Identity:	44/189 - (23%)
Similarity:	79/189 - (41%)	Gaps:	47/189 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   340 CCLWNSMAPEQLWILNPRKLLSRQIDPS-------IPTLNAETNKLSPEEGQSFLTKKD---CWI 394
            ||    ..|..|........||:.::.:       :..:.|:..:|.....::..|:.|   |.|
Zfish     6 CC----HLPGSLCDCTGNAALSKTVEEADNRRAQYVTQVTAKDGRLLSTVIKALGTQSDRPTCRI 66

  Fly   395 CYDSD---KPEPLIQPCRCTGDVSSVHHECLKRWLVESCSNSEAQLSCKVCGHPYEIEKSKK--L 454
            |::..   ..|.|:.||.|||.:.:||..||::||  |.||:.   .|::|...:.||:..:  .
Zfish    67 CHEGQDVCNSEGLLSPCDCTGTLGTVHKSCLEKWL--SSSNTS---YCELCHTEFTIERRPRPLT 126

  Fly   455 EW--DKGFTIQHWSKTVILITLMCVTGATAWVVIQMYVDPLVRVMTVGIAVLIGYVCVK 511
            ||  |.|   ....|..:...::|.          :::.||        |.:.|::|::
Zfish   127 EWLRDPG---PRNEKRTLFCDMVCF----------LFITPL--------AAISGWLCLR 164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2991	NP_608725.1	SSM4	389..>494	CDD:227510	31/114 (27%)
CG2991	NP_608725.1	RING_CH-C4HC3_MARCH	392..443	CDD:319409	20/53 (38%)
march2	NP_001038255.2	RINGv	64..113	CDD:128983	20/53 (38%)
march2	NP_001038255.2	Vpu	176..>220	CDD:109608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810