DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2991 and Marchf11

DIOPT Version :9

Sequence 1:	NP_608725.1	Gene:	CG2991 / 33488	FlyBaseID:	FBgn0031474	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_001095298.1	Gene:	Marchf11 / 499558	RGDID:	1559945	Length:	398	Species:	Rattus norvegicus

Alignment Length:	149	Identity:	37/149 - (24%)
Similarity:	64/149 - (42%)	Gaps:	27/149 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   392 CWICYDSDKPEPLIQPCRCTGDVSSVHHECLKRWLVESCSNSEAQLSCKVCGHPYE---IEKSKK 453
            |.||:...:...|:.||||.|.|...|..||.:|:.|     ....:|::|.:.|.   |:..:.
  Rat   166 CKICFQGAEQGELLNPCRCDGSVRYTHQLCLLKWISE-----RGSWTCELCCYRYHVTAIKMKQP 225

  Fly   454 LEWDKGFTIQHWSK----TVILITLMCVTGAT--AWVVIQMYV-----DPLVRVMTVGIAVLIGY 507
            .:| :..:|....|    .|||.:|..:...|  .|.....|.     |.|.:: ..|   :.|:
  Rat   226 CQW-QSISITLVEKVQMIAVILGSLFLIASVTWLLWSAFSPYAVWQRKDILFQI-CYG---MYGF 285

  Fly   508 VCVKCLGENTVVAYQRAKV 526
            :.:.|:|   ::.::.|.|
  Rat   286 MDLVCIG---LIVHEGAAV 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2991	NP_608725.1	SSM4	389..>494	CDD:227510	30/115 (26%)
CG2991	NP_608725.1	RING_CH-C4HC3_MARCH	392..443	CDD:319409	16/50 (32%)
Marchf11	NP_001095298.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..158
		RING_CH-C4HC3_MARCH4_like	165..215	CDD:319614	17/53 (32%)
		YXXL motif	367..370
		PDZ-binding	395..398
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810