DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2991 and MARCHF8

DIOPT Version :9

Sequence 1:NP_608725.1 Gene:CG2991 / 33488 FlyBaseID:FBgn0031474 Length:562 Species:Drosophila melanogaster
Sequence 2:NP_001269795.1 Gene:MARCHF8 / 220972 HGNCID:23356 Length:573 Species:Homo sapiens


Alignment Length:250 Identity:65/250 - (26%)
Similarity:101/250 - (40%) Gaps:59/250 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   359 LLSRQIDPSIPTLNAETNKLSPEEGQSFLTKKD-CWICY-DSDKPEPLIQPCRCTGDVSSVHHEC 421
            |.|.:.|..:...:..:.||.|....|  |..| |.||: :.|...|||.||.|||.:..||..|
Human   330 LCSTEKDSDLDCPSPFSEKLPPISPVS--TSGDVCRICHCEGDDESPLITPCHCTGSLHFVHQAC 392

  Fly   422 LKRWLVESCSNSEAQLSCKVCGHPYEIE-KSKKL-EWDKGFTIQHWSK---------TVILITLM 475
            |::|:..|.:.     .|::|.:.:.:| |.|.| :|:|   :|..|.         |..:|.:.
Human   393 LQQWIKSSDTR-----CCELCKYEFIMETKLKPLRKWEK---LQMTSSERRKIMCSVTFHVIAIT 449

  Fly   476 CVTGATAWVVIQMYVDPLVRVMTVGI----------AVLIG------YVCVKC----------LG 514
            ||.. :.:|:|....:.:.:....||          .|.||      ::.|:|          ..
Human   450 CVVW-SLYVLIDRTAEEIKQGQATGILEWPFWTKLVVVAIGFTGGLLFMYVQCKVYVQLWKRLKA 513

  Fly   515 ENTVVAYQRA-KVSSINI-----VTSSEMEKLH--TIC-EEVSASTSAEAVRAGA 560
            .|.|:..|.. :.|..||     :|....|..|  .|| .:.::|...|....||
Human   514 YNRVIYVQNCPETSKKNIFEKSPLTEPNFENKHGYGICHSDTNSSCCTEPEDTGA 568

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2991NP_608725.1 SSM4 389..>494 CDD:227510 35/117 (30%)
RING_CH-C4HC3_MARCH 392..443 CDD:319409 19/51 (37%)
MARCHF8NP_001269795.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 22..72
RINGv 361..409 CDD:128983 19/52 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5183
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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