DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2991 and Marchf9

DIOPT Version :9

Sequence 1:	NP_608725.1	Gene:	CG2991 / 33488	FlyBaseID:	FBgn0031474	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_001028434.1	Gene:	Marchf9 / 216438	MGIID:	2446144	Length:	348	Species:	Mus musculus

Alignment Length:	161	Identity:	40/161 - (24%)
Similarity:	66/161 - (40%)	Gaps:	31/161 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   385 SFLTKKDCWICYDSDKPEPLIQPCRCTGDVSSVHHECLKRWLVESCSNSEAQLSCKVCGHPYE-- 447
            |.|....|.||:...:...|:.||||.|.|...|..||.||:.|     ....||::|...|:
Mouse   103 SGLRTPQCRICFQGPEQGELLSPCRCDGSVRCTHQPCLIRWISE-----RGSWSCELCYFKYQVL 162

  Fly   448 -IEKSKKLEWDKGFTIQHWSKTV--------ILITLMCVTGATAWVVIQMYVDPLVRVMTVGIAV 503
             |.....|:|      |..|.||        |::..:.:..:.:| :|...:.|..:.....:..
Mouse   163 AISTKNPLQW------QAISLTVIEKVQIAAIVLGSLFLVASISW-LIWSSLSPSAKWQRQDLLF 220

  Fly   504 LI-----GYVCVKCLGENTVVAYQRAKVSSI 529
            .|     |::.|.|:|   ::.::.:.|..|
Mouse   221 QICYGMYGFMDVVCIG---LIVHEGSSVYRI 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2991	NP_608725.1	SSM4	389..>494	CDD:227510	31/115 (27%)
CG2991	NP_608725.1	RING_CH-C4HC3_MARCH	392..443	CDD:319409	18/50 (36%)
Marchf9	NP_001028434.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	48..96
		RINGv	109..155	CDD:128983	18/50 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	272..304
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	328..348
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810