DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2991 and marc-4

DIOPT Version :9

Sequence 1:	NP_608725.1	Gene:	CG2991 / 33488	FlyBaseID:	FBgn0031474	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_001348646.1	Gene:	marc-4 / 171616	WormBaseID:	WBGene00016903	Length:	317	Species:	Caenorhabditis elegans

Alignment Length:	202	Identity:	52/202 - (25%)
Similarity:	83/202 - (41%)	Gaps:	47/202 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   347 APEQLWILNPRKLLSRQ---IDPSIPT-------LNAE---TNKLSPEEGQSFLTKKDCWICY-- 396
            ||.|...|....|:..:   ||.|..|       |.|.   ::|||.:...:.:    |.||:
Worm    26 APSQPNRLEKEPLIDEETDMIDESRATYWKGCEFLKASGLYSSKLSLQSASANM----CRICHTS 86

  Fly   397 DSDKPEPLIQPCRCTGDVSSVHHECLKRWLVESCSNSEAQLSCKVCGHPY---EIEKSKKLEWDK 458
            .|.:..|||.||||:|.:..||..|:.|||..|.........|::||:.|   .|.:.|.|.
Worm    87 TSTRSNPLISPCRCSGTLLFVHKACVVRWLEMSTRKMVPSPRCELCGYDYRRGNIFQMKSLH--- 148

  Fly   459 GFTIQHWSKTVILITLMCVTGATAWVVIQMYVDPLVRVMTVGIAVLIGYVCVKCLGENTVVAYQR 523
               :.|..::..|:.::.                   ::||.|.:..||..::.:.||.::..:.
Worm   149 ---VPHVDRSSCLLNVLF-------------------LITVLIMIFCGYFTIQFIQENALLKRRL 191

  Fly   524 AKVSSIN 530
            ...||.|
Worm   192 FAHSSTN 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2991	NP_608725.1	SSM4	389..>494	CDD:227510	28/109 (26%)
CG2991	NP_608725.1	RING_CH-C4HC3_MARCH	392..443	CDD:319409	20/52 (38%)
marc-4	NP_001348646.1	RING_CH-C4HC3_MARCH	80..133	CDD:319409	20/52 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810