DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3104 and MBP1

DIOPT Version :9

Sequence 1:	NP_001259969.1	Gene:	CG3104 / 33486	FlyBaseID:	FBgn0031473	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_010227.1	Gene:	MBP1 / 851503	SGDID:	S000002214	Length:	833	Species:	Saccharomyces cerevisiae

Alignment Length:	223	Identity:	53/223 - (23%)
Similarity:	89/223 - (39%)	Gaps:	55/223 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 LDQGADPNSRRLTGTTPLFFAAQGGHLDVVKILIKAGASVDTPSADGGTPLFVACQGGHVKIVRE 127
            :|...||...     |...:|...|:|.:.:.|.:||.|:.:.::.|.|||           :|.
Yeast   387 IDAPIDPELH-----TAFHWACSMGNLPIAEALYEAGTSIRSTNSQGQTPL-----------MRS 435

  Fly   128 LLDCGANVNAHMKDRATPVFISAQNGHRTVLSLLIQAGAEID--IKRIDGATPLWIAAQMGQDHI 190
            .|    ..|::.:.....:|   |..|.||..:..|:...|.  :|| ...||..:       :.
Yeast   436 SL----FHNSYTRRTFPRIF---QLLHETVFDIDSQSQTVIHHIVKR-KSTTPSAV-------YY 485

  Fly   191 CKVLLQNGANVDTVRCDGATPLFKAAHKGHAAVITVLLKYRPNLGQLPNGESALHAAAMFGHMTV 255
            ..|:|.        :....:|.::         |.:||.     .|..||::|||.|:..|.:..
Yeast   486 LDVVLS--------KIKDFSPQYR---------IELLLN-----TQDKNGDTALHIASKNGDVVF 528

  Fly   256 CKQLVAAGSDVLLKNHDGLTALQLAHQQ 283
            ...||..|:...:.|.:||||.::.:||
Yeast   529 FNTLVKMGALTTISNKEGLTANEIMNQQ 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3104	NP_001259969.1	Ank_2	<13..72	CDD:289560	3/8 (38%)
		ANK repeat	13..40	CDD:293786
		ANK	37..162	CDD:238125	23/98 (23%)
		ANK repeat	42..73	CDD:293786	3/9 (33%)
		Ank_2	47..137	CDD:289560	17/73 (23%)
		ANK repeat	75..106	CDD:293786	8/30 (27%)
		ANK	103..228	CDD:238125	22/126 (17%)
		ANK repeat	108..137	CDD:293786	6/28 (21%)
		Ank_2	113..202	CDD:289560	17/90 (19%)
		ANK repeat	141..171	CDD:293786	7/31 (23%)
		ANK	169..292	CDD:238125	28/117 (24%)
		ANK repeat	174..204	CDD:293786	4/29 (14%)
		Ank_2	179..270	CDD:289560	17/90 (19%)
		ANK repeat	207..237	CDD:293786	4/29 (14%)
		ANK repeat	239..270	CDD:293786	10/30 (33%)
MBP1	NP_010227.1	KilA-N	22..93	CDD:367917
		ANKYR	363..544	CDD:223738	46/209 (22%)
		ANK repeat	396..425	CDD:293786	8/33 (24%)
		ANK repeat	427..510	CDD:293786	24/130 (18%)
		ANK repeat	512..543	CDD:293786	10/30 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4177
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900