DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3104 and TNKS2

DIOPT Version :9

Sequence 1:NP_001259969.1 Gene:CG3104 / 33486 FlyBaseID:FBgn0031473 Length:321 Species:Drosophila melanogaster
Sequence 2:XP_005270242.2 Gene:TNKS2 / 80351 HGNCID:15677 Length:1190 Species:Homo sapiens


Alignment Length:324 Identity:95/324 - (29%)
Similarity:151/324 - (46%) Gaps:51/324 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 QLHMAAMRGDEVALLRVLDSGKVHVDCKDEDG--TTPLILAAAGGHTYCVMELLDQGADPNSRRL 74
            :|..:|..|:|..::.:|.  .::|:|...||  :|||.|||.......|..||..|||.:::..
Human   201 ELLESARSGNEEKMMALLT--PLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDK 263

  Fly    75 TGTTPLFFAAQGGHLDVVKILIKAGASVDTPSADGGTPLFVACQGGHVKIVRELLDCGAN---VN 136
            ....||..|...||.:|.::|:|.||.|:.......|||..|.....|::...||..||:   :|
Human   264 GDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLN 328

  Fly   137 AH------------MKDRATPVFISAQNGHRTVLSLLIQAGAEIDIKRI---------------D 174
            .|            :|:|....|    .||.     |:||..|.|:.||               .
Human   329 CHNKSAIDLAPTPQLKERLAYEF----KGHS-----LLQAAREADVTRIKKHLSLEMVNFKHPQT 384

  Fly   175 GATPLWIAAQM---GQDHICKVLLQNGANVDTVRCDGATPLFKAAHKGHAAVITVLLKYRPNLGQ 236
            ..|.|..||..   .:..||::||:.|||::....:..|||..|:.|.|..|:.|::|:...:..
Human   385 HETALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNA 449

  Fly   237 LPN-GESALHAAAMFGHMTVCKQLVAAGSDVLLKNHDGLTALQLAHQQKYTSICDYLQERIRTM 299
            |.| |:::||.||..||:..|:.|::.|.|..:.:..|.||||:.::    ::...||:.:..:
Human   450 LDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNE----NVQQLLQDLVHNL 509

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3104NP_001259969.1 Ank_2 <13..72 CDD:289560 21/60 (35%)
ANK repeat 13..40 CDD:293786 7/26 (27%)
ANK 37..162 CDD:238125 42/141 (30%)
ANK repeat 42..73 CDD:293786 14/32 (44%)
Ank_2 47..137 CDD:289560 30/92 (33%)
ANK repeat 75..106 CDD:293786 11/30 (37%)
ANK 103..228 CDD:238125 42/157 (27%)
ANK repeat 108..137 CDD:293786 9/31 (29%)
Ank_2 113..202 CDD:289560 32/121 (26%)
ANK repeat 141..171 CDD:293786 9/29 (31%)
ANK 169..292 CDD:238125 41/141 (29%)
ANK repeat 174..204 CDD:293786 11/32 (34%)
Ank_2 179..270 CDD:289560 32/94 (34%)
ANK repeat 207..237 CDD:293786 9/29 (31%)
ANK repeat 239..270 CDD:293786 12/31 (39%)
TNKS2XP_005270242.2 Ank_2 28..142 CDD:372319
ANK repeat 60..109 CDD:293786
PHA02876 <94..>479 CDD:165207 87/288 (30%)
ANK repeat 111..142 CDD:293786
ANK repeat 144..175 CDD:293786
ANK repeat 234..262 CDD:293786 12/27 (44%)
ANK repeat 264..295 CDD:293786 11/30 (37%)
ANK repeat 297..328 CDD:293786 9/30 (30%)
ANK repeat 386..418 CDD:293786 11/31 (35%)
ANK repeat 420..451 CDD:293786 9/30 (30%)
ANK repeat 453..482 CDD:293786 11/28 (39%)
PHA03095 540..>826 CDD:222980
ANK repeat 552..580 CDD:293786
ANK repeat 582..613 CDD:293786
ANK repeat 615..646 CDD:293786
ANK repeat 668..698 CDD:293786
ANK repeat 705..733 CDD:293786
ANK repeat 735..766 CDD:293786
ANK repeat 768..799 CDD:293786
SAM_tankyrase1,2 895..960 CDD:188923
tankyrase_like 962..1184 CDD:238718
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4177
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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