DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3104 and Ankrd65

DIOPT Version :9

Sequence 1:	NP_001259969.1	Gene:	CG3104 / 33486	FlyBaseID:	FBgn0031473	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_001102897.1	Gene:	Ankrd65 / 680734	RGDID:	1588232	Length:	365	Species:	Rattus norvegicus

Alignment Length:	307	Identity:	107/307 - (34%)
Similarity:	145/307 - (47%)	Gaps:	25/307 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KETPSD-----------VQLHMAAMRGDEVALLRVLDSGKVHVDCKDEDGTTPLILAAAGGHTYC 58
            :|||:|           ..|..|...|....::::|..| ..|:.:|..|.|||.||...||...
  Rat    18 EETPADKTDRPLTPQGWSTLFQAVWWGAPSLVMQLLRQG-ASVEERDHTGRTPLHLAVMRGHAPL 81

  Fly    59 VMELLDQGADPNSRRLTGTTPLFFAAQGGHLDVVKILIKAGASVDTP-SADGGTPLFVACQGGHV 122
            |..||.:||...:...||.|||..||..||.:|.::|::.|||...| |..|.|||..|...|..
  Rat    82 VRLLLQRGALAGAVDHTGRTPLHEAAWHGHSNVAELLLRRGASAAAPCSQTGLTPLHGAAALGRT 146

  Fly   123 KIVRELLDCGANVNAHMKDRA--TPVFISAQNGHRTVLSLLIQAGAEIDIKRIDGATPLWIAAQM 185
            .:|........:| ..:||..  |....:|..|...||.|| .||..:|   :|||  |.::|..
  Rat   147 LLVTCFTAAPDSV-PDVKDIRGWTATHWAAACGQLPVLELL-TAGGSVD---LDGA--LLVSAVA 204

  Fly   186 GQDHICKVLLQNGANVDTVRCDGATPLFKAAHKGHAAVITVLLKY--RPNLGQLPNGESALHAAA 248
            |.....::||..||.||.:...|||.|..||..||...|.|||.:  .||:.. .|..||||.||
  Rat   205 GSASALRLLLTLGAKVDALDSTGATALGLAAGLGHHQEIEVLLGHGADPNIRD-RNNRSALHRAA 268

  Fly   249 MFGHMTVCKQLVAAGSDVLLKNHDGLTALQLAHQQKYTSICDYLQER 295
            ..|.:...:.|||.|:||..::..|||.|..|.:..:..:..:|.:|
  Rat   269 SGGCLRAIQLLVAKGTDVDARDSLGLTPLHYAARGGHREVVSHLLDR 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3104	NP_001259969.1	Ank_2	<13..72	CDD:289560	20/58 (34%)
		ANK repeat	13..40	CDD:293786	6/26 (23%)
		ANK	37..162	CDD:238125	46/127 (36%)
		ANK repeat	42..73	CDD:293786	13/30 (43%)
		Ank_2	47..137	CDD:289560	34/90 (38%)
		ANK repeat	75..106	CDD:293786	15/31 (48%)
		ANK	103..228	CDD:238125	44/127 (35%)
		ANK repeat	108..137	CDD:293786	8/28 (29%)
		Ank_2	113..202	CDD:289560	27/90 (30%)
		ANK repeat	141..171	CDD:293786	11/31 (35%)
		ANK	169..292	CDD:238125	46/124 (37%)
		ANK repeat	174..204	CDD:293786	12/29 (41%)
		Ank_2	179..270	CDD:289560	37/92 (40%)
		ANK repeat	207..237	CDD:293786	14/31 (45%)
		ANK repeat	239..270	CDD:293786	14/30 (47%)
Ankrd65	NP_001102897.1	ANK	33..149	CDD:238125	42/116 (36%)
		ANK repeat	33..63	CDD:293786	6/30 (20%)
		Ank_2	37..123	CDD:289560	31/86 (36%)
		ANK repeat	65..96	CDD:293786	13/30 (43%)
		ANK repeat	98..123	CDD:293786	11/24 (46%)
		ANK repeat	197..224	CDD:293786	10/28 (36%)
		Ank_2	198..290	CDD:289560	37/92 (40%)
		ANK	221..346	CDD:238125	36/96 (38%)
		ANK repeat	227..257	CDD:293786	14/29 (48%)
		ANK repeat	259..290	CDD:293786	14/30 (47%)
		Ank_2	264..355	CDD:289560	18/52 (35%)
		ANK repeat	292..323	CDD:293786	7/24 (29%)
		ANK repeat	325..355	CDD:293786
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4177
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53592
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910