DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3104 and HACE1

DIOPT Version :9

Sequence 1:NP_001259969.1 Gene:CG3104 / 33486 FlyBaseID:FBgn0031473 Length:321 Species:Drosophila melanogaster
Sequence 2:NP_065822.2 Gene:HACE1 / 57531 HGNCID:21033 Length:909 Species:Homo sapiens


Alignment Length:184 Identity:65/184 - (35%)
Similarity:97/184 - (52%) Gaps:2/184 - (1%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 LHMAAMRGDEVALLRVLDSGKVHVDCKDEDGTTPLILAAAGGHTYCVMELLDQGADPNSRRLTGT 77
            ||:||..|....|:.:|..| .:.:.:|..|.|||.|||..|...|:.:||:..||.|.....|.
Human    69 LHIAANCGSVECLVLLLKKG-ANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGL 132

  Fly    78 TPLFFAAQGGHLDVVKILIKAGASVDTPSADGGTPLFVACQGGHVKIVRELLDCGANVNAHMKDR 142
            |.:.:.|..|..:::..|::..:.||...|.|.|.|.||||.||...|:.|||.||::|......
Human   133 TAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSG 197

  Fly   143 ATPVFISAQNGHRTVLSLLIQAGAEIDIKRIDGATPLWIAAQMGQDHICKVLLQ 196
            |||::.:..:|.|....:|:..||:. :...:|.|||.:..|.|....|:||:|
Human   198 ATPLYFACSHGQRDTAQILLLRGAKY-LPDKNGVTPLDLCVQGGYGETCEVLIQ 250

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3104NP_001259969.1 Ank_2 <13..72 CDD:289560 23/58 (40%)
ANK repeat 13..40 CDD:293786 8/26 (31%)
ANK 37..162 CDD:238125 44/124 (35%)
ANK repeat 42..73 CDD:293786 14/30 (47%)
Ank_2 47..137 CDD:289560 34/89 (38%)
ANK repeat 75..106 CDD:293786 7/30 (23%)
ANK 103..228 CDD:238125 36/94 (38%)
ANK repeat 108..137 CDD:293786 15/28 (54%)
Ank_2 113..202 CDD:289560 32/84 (38%)
ANK repeat 141..171 CDD:293786 8/29 (28%)
ANK 169..292 CDD:238125 10/28 (36%)
ANK repeat 174..204 CDD:293786 10/23 (43%)
Ank_2 179..270 CDD:289560 7/18 (39%)
ANK repeat 207..237 CDD:293786
ANK repeat 239..270 CDD:293786
HACE1NP_065822.2 Ank_2 <27..>283 CDD:330894 65/184 (35%)
ANK 1 64..93 8/24 (33%)
ANK repeat 66..95 CDD:293786 8/26 (31%)
ANK 92..217 CDD:238125 44/124 (35%)
ANK repeat 97..128 CDD:293786 14/30 (47%)
ANK 2 97..126 13/28 (46%)
ANK repeat 130..161 CDD:293786 7/30 (23%)
ANK 3 130..159 6/28 (21%)
ANK repeat 163..194 CDD:293786 16/30 (53%)
ANK 4 163..192 15/28 (54%)
ANK 5 196..226 8/30 (27%)
ANK repeat 196..221 CDD:293786 6/24 (25%)
ANK 6 228..257 10/23 (43%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 398..433
HECTc 554..903 CDD:238033
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4177
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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