DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG3104 and ank2a

DIOPT Version :9

Sequence 1:NP_001259969.1 Gene:CG3104 / 33486 FlyBaseID:FBgn0031473 Length:321 Species:Drosophila melanogaster
Sequence 2:XP_021331690.1 Gene:ank2a / 568926 ZFINID:ZDB-GENE-111215-3 Length:4856 Species:Danio rerio


Alignment Length:317 Identity:106/317 - (33%)
Similarity:158/317 - (49%) Gaps:43/317 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 TPSDVQLHMAAMRGDEVALLRVLDSGKVHVDCKDEDGTTPLILAAAGGHTYCVMELLDQGADPNS 71
            ||    ||:|:.||:...:..:||.|. .:|.|..||.|||..||..||...|..||::||...:
Zfish   285 TP----LHVASKRGNTNMIALLLDRGS-QIDAKTRDGLTPLHCAARSGHDSAVEILLEKGAPILA 344

  Fly    72 RRLTGTTPLFFAAQGGHLDVVKILIKAGASVD------------------------------TPS 106
            |...|.:||..:|||.|::.||.|::..|.||                              .|:
Zfish   345 RTKNGLSPLHMSAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKKANPN 409

  Fly   107 A---DGGTPLFVACQGGHVKIVRELLDCGANVNAHMKDRATPVFISAQNGHRTVLSLLIQAGAEI 168
            |   :|.|||.:||:...||::..|:..||::.|..:...||:.:||..||..::.||:|.||..
Zfish   410 ARALNGFTPLHIACKKNRVKVMELLVKYGASIQAITESGLTPIHVSAFMGHLNIVLLLLQNGASP 474

  Fly   169 DIKRIDGATPLWIAAQMGQDHICKVLLQNGANVDTVRCDGATPLFKAAHKGHAAVITVLLKY--R 231
            |:..|.|.|.|.:||:.||..:.:.||:|||.||.:..:..|||..|:..|...::.:||::  .
Zfish   475 DVCNIRGETALHMAARAGQMEVVRCLLRNGALVDAMAREDQTPLHIASRLGQTEIVQLLLQHMAH 539

  Fly   232 PNLGQLPNGESALHAAAMFGHMTVCKQLVAAGSDVLLKNHDGLTALQLAHQQKYTSI 288
            |: ....||.:.||.:|..|.:.....|:.||:...|....|.|.|.:|  .||.|:
Zfish   540 PD-ASTTNGYTPLHISAREGQVETAAVLLEAGASHSLATKKGFTPLHVA--AKYGSL 593

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3104NP_001259969.1 Ank_2 <13..72 CDD:289560 24/58 (41%)
ANK repeat 13..40 CDD:293786 9/26 (35%)
ANK 37..162 CDD:238125 51/157 (32%)
ANK repeat 42..73 CDD:293786 14/30 (47%)
Ank_2 47..137 CDD:289560 37/122 (30%)
ANK repeat 75..106 CDD:293786 13/60 (22%)
ANK 103..228 CDD:238125 47/157 (30%)
ANK repeat 108..137 CDD:293786 11/28 (39%)
Ank_2 113..202 CDD:289560 34/88 (39%)
ANK repeat 141..171 CDD:293786 12/29 (41%)
ANK 169..292 CDD:238125 41/122 (34%)
ANK repeat 174..204 CDD:293786 14/29 (48%)
Ank_2 179..270 CDD:289560 30/92 (33%)
ANK repeat 207..237 CDD:293786 8/31 (26%)
ANK repeat 239..270 CDD:293786 10/30 (33%)
ank2aXP_021331690.1 ANK <40..98 CDD:238125
ANK repeat 44..75 CDD:293786
ANK 74..197 CDD:238125
ANK repeat 77..108 CDD:293786
ANK repeat 110..141 CDD:293786
ANK repeat 143..168 CDD:293786
Ank_4 206..270 CDD:316185
ANK repeat 209..236 CDD:293786
ANK 248..369 CDD:238125 36/88 (41%)
ANK repeat 249..280 CDD:293786
ANK repeat 282..313 CDD:293786 11/32 (34%)
ANK 310..435 CDD:238125 40/124 (32%)
ANK repeat 315..346 CDD:293786 14/30 (47%)
ANK repeat 348..379 CDD:293786 13/30 (43%)
ANK repeat 381..411 CDD:293786 1/29 (3%)
ANK 409..534 CDD:238125 45/124 (36%)
ANK repeat 414..445 CDD:293786 12/30 (40%)
ANK repeat 447..478 CDD:293786 12/30 (40%)
ANK 475..600 CDD:238125 41/122 (34%)
ANK repeat 480..511 CDD:293786 14/30 (47%)
ANK repeat 513..542 CDD:293786 8/29 (28%)
ANK repeat 546..571 CDD:293786 8/24 (33%)
ANK 578..699 CDD:238125 7/18 (39%)
ANK repeat 579..607 CDD:293786 7/17 (41%)
ANK repeat 612..643 CDD:293786
ANK repeat 645..676 CDD:293786
ANK 673..798 CDD:238125
ANK repeat 678..707 CDD:293786
ANK repeat 711..742 CDD:293786
ANK repeat 744..775 CDD:293786
ANK repeat 777..807 CDD:293786
Ank_4 778..830 CDD:316185
ZU5 999..1136 CDD:128514
DD 3434..3517 CDD:326335
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4177
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.900

Return to query results.
Submit another query.