DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3104 and tnksa

DIOPT Version :9

Sequence 1:	NP_001259969.1	Gene:	CG3104 / 33486	FlyBaseID:	FBgn0031473	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	XP_009293648.1	Gene:	tnksa / 559022	ZFINID:	ZDB-GENE-030131-7450	Length:	1259	Species:	Danio rerio

Alignment Length:	471	Identity:	110/471 - (23%)
Similarity:	170/471 - (36%)	Gaps:	158/471 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSLKKETPSDVQLHMAAMRGDEVALLRVLDSGKVHVDCKDEDGTTPLILAAAGGHTYCVMELLDQ 65
            |:.:|.||    ||.||..|.:..:..:|.:| .:|..:|:.|..||..|.:.||...|..||.|
Zfish   137 MAGRKSTP----LHFAAGFGRKDVVEHLLQTG-ANVHARDDGGLIPLHNACSFGHAEVVSLLLCQ 196

  Fly    66 GADPNSRRLTGTTPLFFAAQGGHLDVVKILIKAGASVDTPSADG--------------------- 109
            |||||:|.....|||..||..|.:||..:|::.||..:..:.||
Zfish   197 GADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKK 261

  Fly   110 ----------------------------------------GTPLFVACQGGHVKIVRELLDCGAN 134
                                                    .|||.:|.....|:||:.||..||:
Zfish   262 DELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTSQKMLSTPLHLAAGYNRVRIVQLLLQHGAD 326

  Fly   135 VNAHMKDRATPVFISAQNGHRTVLSLLIQAGAEIDIKRIDGATPLWIAAQMGQDHICKVLLQNGA 199
            |:|..|....|:..:...||..|..||::.||.::...:...|||..||...:..:|.:||.:||
Zfish   327 VHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGA 391

  Fly   200 NVDTVRCDG-------------------------------------------------------- 208
            :...|.|.|
Zfish   392 DPTLVNCHGKSAVDMAPTPELKERLTYEFKGHSLLQAAREADMTKVKKTLALEIINFKHPQTHET 456

  Fly   209 ----------------------------------ATPLFKAAHKGHAAVITVLLKYRPNLGQLPN 239
                                              .|||..||.:.|..::.||.|:...:..:..
Zfish   457 ALHCAVVSPHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDILEVLQKHGAKMNAVDT 521

  Fly   240 -GESALHAAAMFGHMTVCKQLVAAGSDVLLKNHDGLTALQLAHQQKYTSICDYLQERIRTMVARS 303
             |::|||.||:.||:..|:.|::.|:|..:.:..|.||.|:.::.....:.:.:..|...:..|.
Zfish   522 LGQTALHRAALAGHLQTCRLLLSYGADPAIVSLQGFTAAQMGNEAVQQILNENIPVRNSDVDYRL 586

  Fly   304 AKAMATSGVSSTVKTM 319
            .:| |.:|...|||.:
Zfish   587 LEA-AKAGDLDTVKQL 601

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3104	NP_001259969.1	Ank_2	<13..72	CDD:289560	24/58 (41%)
		ANK repeat	13..40	CDD:293786	8/26 (31%)
		ANK	37..162	CDD:238125	49/185 (26%)
		ANK repeat	42..73	CDD:293786	15/30 (50%)
		Ank_2	47..137	CDD:289560	39/150 (26%)
		ANK repeat	75..106	CDD:293786	11/30 (37%)
		ANK	103..228	CDD:238125	44/275 (16%)
		ANK repeat	108..137	CDD:293786	14/89 (16%)
		Ank_2	113..202	CDD:289560	30/88 (34%)
		ANK repeat	141..171	CDD:293786	8/29 (28%)
		ANK	169..292	CDD:238125	38/213 (18%)
		ANK repeat	174..204	CDD:293786	10/29 (34%)
		Ank_2	179..270	CDD:289560	32/181 (18%)
		ANK repeat	207..237	CDD:293786	10/119 (8%)
		ANK repeat	239..270	CDD:293786	12/31 (39%)
tnksa	XP_009293648.1	Ank_4	111..161	CDD:290365	9/27 (33%)
		ANK	133..247	CDD:238125	42/114 (37%)
		ANK repeat	143..171	CDD:293786	10/32 (31%)
		Ank_2	145..237	CDD:289560	36/92 (39%)
		ANK repeat	173..204	CDD:293786	15/30 (50%)
		ANK	201..387	CDD:238125	43/185 (23%)
		ANK repeat	206..237	CDD:293786	11/30 (37%)
		ANK repeat	303..331	CDD:293786	13/27 (48%)
		Ank_2	305..397	CDD:289560	30/91 (33%)
		ANK repeat	333..364	CDD:293786	8/30 (27%)
		ANK repeat	366..397	CDD:293786	10/30 (33%)
		ANK repeat	455..487	CDD:293786	0/31 (0%)
		Ank_2	458..552	CDD:289560	21/93 (23%)
		ANK	484..669	CDD:238125	33/119 (28%)
		ANK repeat	489..520	CDD:293786	9/30 (30%)
		ANK repeat	522..552	CDD:293786	12/29 (41%)
		Ank_2	527..646	CDD:289560	22/76 (29%)
		ANK	608..733	CDD:238125
		ANK repeat	618..646	CDD:293786
		Ank_2	620..712	CDD:289560
		ANK repeat	648..679	CDD:293786
		ANK repeat	681..712	CDD:293786
		ANK repeat	734..764	CDD:293786
		Ank_4	735..789	CDD:290365
		ANK	761..885	CDD:238125
		ANK repeat	768..799	CDD:293786
		Ank_2	773..865	CDD:289560
		ANK repeat	801..832	CDD:293786
		ANK repeat	834..865	CDD:293786
		SAM_tankyrase1,2	958..1021	CDD:188923
		SAM	962..1019	CDD:197735
		tankyrase_like	1023..1245	CDD:238718
		PARP	1037..1240	CDD:279038
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4177
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810