DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3104 and Hace1

DIOPT Version :9

Sequence 1:	NP_001259969.1	Gene:	CG3104 / 33486	FlyBaseID:	FBgn0031473	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	XP_006256657.1	Gene:	Hace1 / 361866	RGDID:	1306114	Length:	916	Species:	Rattus norvegicus

Alignment Length:	184	Identity:	65/184 - (35%)
Similarity:	96/184 - (52%)	Gaps:	2/184 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LHMAAMRGDEVALLRVLDSGKVHVDCKDEDGTTPLILAAAGGHTYCVMELLDQGADPNSRRLTGT 77
            ||:||..|....|:.:|..| .:.:.:|..|.|||.|||..|...|:.:||:..||.|.....|.
  Rat    69 LHIAANCGSVECLVLLLKKG-ANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGL 132

  Fly    78 TPLFFAAQGGHLDVVKILIKAGASVDTPSADGGTPLFVACQGGHVKIVRELLDCGANVNAHMKDR 142
            |.:.:.|..|..:::..|::....||...|.|.|.|.||||.||...|:.|||.||::|......
  Rat   133 TAIHWLAVNGRTELLHDLVQHVTDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVAG 197

  Fly   143 ATPVFISAQNGHRTVLSLLIQAGAEIDIKRIDGATPLWIAAQMGQDHICKVLLQ 196
            |||::.:..:|.|....:|:..||:. :...:|.|||.:..|.|....|:||:|
  Rat   198 ATPLYFACSHGQRDTAQILLLRGAKY-LPDKNGVTPLDLCVQGGYGQTCEVLIQ 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3104	NP_001259969.1	Ank_2	<13..72	CDD:289560	23/58 (40%)
		ANK repeat	13..40	CDD:293786	8/26 (31%)
		ANK	37..162	CDD:238125	44/124 (35%)
		ANK repeat	42..73	CDD:293786	14/30 (47%)
		Ank_2	47..137	CDD:289560	34/89 (38%)
		ANK repeat	75..106	CDD:293786	7/30 (23%)
		ANK	103..228	CDD:238125	36/94 (38%)
		ANK repeat	108..137	CDD:293786	15/28 (54%)
		Ank_2	113..202	CDD:289560	32/84 (38%)
		ANK repeat	141..171	CDD:293786	8/29 (28%)
		ANK	169..292	CDD:238125	10/28 (36%)
		ANK repeat	174..204	CDD:293786	10/23 (43%)
		Ank_2	179..270	CDD:289560	7/18 (39%)
		ANK repeat	207..237	CDD:293786
		ANK repeat	239..270	CDD:293786
Hace1	XP_006256657.1	ANK repeat	66..95	CDD:293786	8/26 (31%)
		ANK	66..93	CDD:197603	8/24 (33%)
		Ank_2	69..194	CDD:289560	47/125 (38%)
		ANK	92..217	CDD:238125	44/124 (35%)
		ANK repeat	97..128	CDD:293786	14/30 (47%)
		ANK repeat	130..161	CDD:293786	7/30 (23%)
		Ank_2	135..222	CDD:289560	29/86 (34%)
		ANK repeat	163..194	CDD:293786	16/30 (53%)
		ANK repeat	196..221	CDD:293786	6/24 (25%)
		Ank_4	199..249	CDD:290365	15/50 (30%)
		HECTc	561..910	CDD:238033
		HECTc	586..909	CDD:214523
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4177
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900