DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3104 and Ankrd42

DIOPT Version :9

Sequence 1:	NP_001259969.1	Gene:	CG3104 / 33486	FlyBaseID:	FBgn0031473	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	XP_017444434.1	Gene:	Ankrd42 / 293117	RGDID:	1310789	Length:	522	Species:	Rattus norvegicus

Alignment Length:	318	Identity:	82/318 - (25%)
Similarity:	138/318 - (43%)	Gaps:	60/318 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 HMAAMRGDEVALLRVLDSGKVHVDCKDEDGTTPLILAAAGGHTYCVMELLDQGADPNSRRLTGTT 78
            |:||:||.:..|..::.:| .::..:|:.|.||:.|||..||::.:..:|..|.||:........
  Rat   104 HVAAIRGQDACLQALIING-ANLATQDDRGCTPVHLAATHGHSFSLQVMLRSGVDPSVTDKREWR 167

  Fly    79 PLFFAAQGGHLDVVKILIKAGASVDTPSADGGTPLFVACQGGHVKIVRELLDCGANVNAHMKDRA 143
            |:.:||..|.|..:::|:|.|..::....:|..|:.:|...||:...:.||   :.||:.:  :|
  Rat   168 PVHYAAFHGRLGCLQLLVKWGCGIEDVDYNGNLPVHLAAMEGHLHCFKFLL---SRVNSAV--QA 227

  Fly   144 TPVFISAQNG-------HRTVLSLLIQ--AGAEIDIKRIDG----ATPLWIAAQMGQDHICKVLL 195
            ...|  ..||       ||.:...::|  .|||.:...:|.    |.|..:||..|...:.|.|:
  Rat   228 LKAF--NDNGENVLDLAHRFLKQNIVQFIQGAEYEGSHLDDQDDLAFPGHVAAFKGDLEMLKKLI 290

  Fly   196 QNGA-NVDTVRCDGATPLFKAAHKGHAAVITVLLKYRPNLGQLPN-----GESALHAAAMFGHMT 254
            .:|. |::....:|:||:.|||.:||...:..|::    :|...|     ||.....|..|.|:.
  Rat   291 DDGVINLNERDENGSTPMHKAAGQGHIDCLQWLVE----MGADSNITNKAGERPSDVAKRFAHLA 351

  Fly   255 VCKQL-----------------------------VAAGSDVLLKNHDGLTALQLAHQQ 283
            ..|.|                             ..|..|:.|...|...|...||::
  Rat   352 AVKLLEGLQKYEIDDIEGDKNHISFFIRHGVEGSTDAKDDLSLSESDKANARMRAHKK 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3104	NP_001259969.1	Ank_2	<13..72	CDD:289560	20/57 (35%)
		ANK repeat	13..40	CDD:293786	7/25 (28%)
		ANK	37..162	CDD:238125	36/131 (27%)
		ANK repeat	42..73	CDD:293786	12/30 (40%)
		Ank_2	47..137	CDD:289560	25/89 (28%)
		ANK repeat	75..106	CDD:293786	8/30 (27%)
		ANK	103..228	CDD:238125	37/138 (27%)
		ANK repeat	108..137	CDD:293786	8/28 (29%)
		Ank_2	113..202	CDD:289560	27/102 (26%)
		ANK repeat	141..171	CDD:293786	10/38 (26%)
		ANK	169..292	CDD:238125	35/154 (23%)
		ANK repeat	174..204	CDD:293786	10/34 (29%)
		Ank_2	179..270	CDD:289560	28/125 (22%)
		ANK repeat	207..237	CDD:293786	10/29 (34%)
		ANK repeat	239..270	CDD:293786	11/64 (17%)
Ankrd42	XP_017444434.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4177
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900