DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3104 and ANK2

DIOPT Version :9

Sequence 1:NP_001259969.1 Gene:CG3104 / 33486 FlyBaseID:FBgn0031473 Length:321 Species:Drosophila melanogaster
Sequence 2:NP_001373103.1 Gene:ANK2 / 287 HGNCID:493 Length:4183 Species:Homo sapiens


Alignment Length:317 Identity:106/317 - (33%)
Similarity:158/317 - (49%) Gaps:43/317 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 TPSDVQLHMAAMRGDEVALLRVLDSGKVHVDCKDEDGTTPLILAAAGGHTYCVMELLDQGADPNS 71
            ||    ||:|:.||:...:..:||.|. .:|.|..||.|||..||..||...|..||::||...:
Human   285 TP----LHVASKRGNTNMVKLLLDRGG-QIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLA 344

  Fly    72 RRLTGTTPLFFAAQGGHLDVVKILIKAGASVD------------------------------TPS 106
            |...|.:||..||||.|::.||.|::..|.||                              .|:
Human   345 RTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPN 409

  Fly   107 A---DGGTPLFVACQGGHVKIVRELLDCGANVNAHMKDRATPVFISAQNGHRTVLSLLIQAGAEI 168
            |   :|.|||.:||:...:|::..|:..||::.|..:...||:.::|..||..::.||:|.||..
Human   410 ARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASP 474

  Fly   169 DIKRIDGATPLWIAAQMGQDHICKVLLQNGANVDTVRCDGATPLFKAAHKGHAAVITVLLKY--R 231
            |:..|.|.|.|.:||:.||..:.:.||:|||.||....:..|||..|:..|...::.:||::  .
Human   475 DVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAH 539

  Fly   232 PNLGQLPNGESALHAAAMFGHMTVCKQLVAAGSDVLLKNHDGLTALQLAHQQKYTSI 288
            |: ....||.:.||.:|..|.:.|...|:.||:...|....|.|.|.:|  .||.|:
Human   540 PD-AATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVA--AKYGSL 593

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3104NP_001259969.1 Ank_2 <13..72 CDD:289560 24/58 (41%)
ANK repeat 13..40 CDD:293786 9/26 (35%)
ANK 37..162 CDD:238125 50/157 (32%)
ANK repeat 42..73 CDD:293786 14/30 (47%)
Ank_2 47..137 CDD:289560 37/122 (30%)
ANK repeat 75..106 CDD:293786 14/60 (23%)
ANK 103..228 CDD:238125 45/157 (29%)
ANK repeat 108..137 CDD:293786 10/28 (36%)
Ank_2 113..202 CDD:289560 32/88 (36%)
ANK repeat 141..171 CDD:293786 11/29 (38%)
ANK 169..292 CDD:238125 42/122 (34%)
ANK repeat 174..204 CDD:293786 14/29 (48%)
Ank_2 179..270 CDD:289560 31/92 (34%)
ANK repeat 207..237 CDD:293786 8/31 (26%)
ANK repeat 239..270 CDD:293786 11/30 (37%)
ANK2NP_001373103.1 Ank_2 35..>311 CDD:423045 10/30 (33%)
ANK repeat 80..111 CDD:293786
ANK repeat 113..144 CDD:293786
ANK repeat 146..171 CDD:293786
Ank_2 202..>444 CDD:423045 53/163 (33%)
ANK repeat 212..247 CDD:293786
ANK repeat 249..280 CDD:293786
ANK repeat 282..313 CDD:293786 11/32 (34%)
ANK repeat 315..345 CDD:293786 14/29 (48%)
ANK repeat 348..379 CDD:293786 14/30 (47%)
ANK repeat 381..411 CDD:293786 1/29 (3%)
ANK repeat 414..445 CDD:293786 11/30 (37%)
PHA03095 421..>706 CDD:222980 59/176 (34%)
ANK repeat 447..478 CDD:293786 11/30 (37%)
ANK repeat 480..511 CDD:293786 14/30 (47%)
ANK repeat 513..542 CDD:293786 8/29 (28%)
ANK repeat 546..571 CDD:293786 9/24 (38%)
Ank_2 578..>802 CDD:423045 7/18 (39%)
ANK repeat 579..604 CDD:293786 7/17 (41%)
ANK repeat 612..643 CDD:293786
ANK repeat 645..676 CDD:293786
ANK repeat 678..707 CDD:293786
ANK repeat 711..742 CDD:293786
ANK repeat 744..775 CDD:293786
ANK repeat 777..806 CDD:293786
Ank_4 778..830 CDD:372654
ZU5 1013..1150 CDD:128514
UPA_2 1371..1500 CDD:375346
PspC_subgroup_1 1549..>1922 CDD:411407
PTZ00449 <1717..2161 CDD:185628
Streccoc_I_II <1843..>2027 CDD:411384
Spc7_N <2493..>2634 CDD:373822
rad2 <3031..>3565 CDD:273166
PRK14949 <3196..>3442 CDD:237863
Death_ank2 3614..3697 CDD:260066
NESP55 <3770..>3884 CDD:115071
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4177
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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