DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3104 and ANK1

DIOPT Version :9

Sequence 1:NP_001259969.1 Gene:CG3104 / 33486 FlyBaseID:FBgn0031473 Length:321 Species:Drosophila melanogaster
Sequence 2:XP_011542792.1 Gene:ANK1 / 286 HGNCID:492 Length:1969 Species:Homo sapiens


Alignment Length:335 Identity:113/335 - (33%)
Similarity:161/335 - (48%) Gaps:40/335 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 LHMAAMRGDEVALLRVLDSGKVHVDCKDEDGTTPLILAAAGGHTYCVMELLDQGADPNSRRLTGT 77
            :|||| :||.:..:|:|......:|....|..|||.:||..||......|||:||.||||.|.|.
Human   374 IHMAA-QGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGF 437

  Fly    78 TPLFFAAQGGHLDVVKILIKAGASVDTPSADGGTPLFVACQGGHVKIVRELLDCGANVNAHMKDR 142
            |||..|.:..|:.|:::|:|.|||:|..:..|.|||.||...||:.||:.||..||:.|......
Human   438 TPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKV 502

  Fly   143 ATPVFISAQNGHRTVLSLLIQAGAEIDIKRIDGATPLWIAAQMGQDHICKVLLQNGANVDTVRCD 207
            .||:.::|:.||..|...|:|..|:::.|..|..|||..||::|..::.|:||:|.||.:.....
Human   503 ETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTA 567

  Fly   208 GATPLFKAAHKGHAAVITVLL-KYRPNLGQLPNGESALHAAAMFGHMTVCKQLV-------AAGS 264
            |.|||..||.:||...:..|| |..........|.:.||.||.:|.:.|.:.|:       |||.
Human   568 GHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGK 632

  Fly   265 DVLLKNH--------------------------DGLTALQLAHQQKYTSICDYLQERIRTMVARS 303
            :.|...|                          :|.|.|.:|.:|....:.     |.......|
Human   633 NGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVA-----RSLLQYGGS 692

  Fly   304 AKAMATSGVS 313
            |.|.:..||:
Human   693 ANAESVQGVT 702

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3104NP_001259969.1 Ank_2 <13..72 CDD:289560 24/58 (41%)
ANK repeat 13..40 CDD:293786 9/26 (35%)
ANK 37..162 CDD:238125 53/124 (43%)
ANK repeat 42..73 CDD:293786 16/30 (53%)
Ank_2 47..137 CDD:289560 42/89 (47%)
ANK repeat 75..106 CDD:293786 13/30 (43%)
ANK 103..228 CDD:238125 47/124 (38%)
ANK repeat 108..137 CDD:293786 14/28 (50%)
Ank_2 113..202 CDD:289560 35/88 (40%)
ANK repeat 141..171 CDD:293786 9/29 (31%)
ANK 169..292 CDD:238125 43/156 (28%)
ANK repeat 174..204 CDD:293786 13/29 (45%)
Ank_2 179..270 CDD:289560 33/98 (34%)
ANK repeat 207..237 CDD:293786 11/30 (37%)
ANK repeat 239..270 CDD:293786 12/37 (32%)
ANK1XP_011542792.1 ANK 47..163 CDD:238125
ANK repeat 47..75 CDD:293786
ANK 108..229 CDD:238125
ANK repeat 109..140 CDD:293786
Ank_2 114..204 CDD:289560
ANK repeat 143..173 CDD:293786
ANK 170..324 CDD:238125
ANK repeat 175..206 CDD:293786
ANK repeat 208..232 CDD:293786
ANK repeat 241..268 CDD:293786
Ank_2 242..333 CDD:289560
ANK 265..390 CDD:238125 7/16 (44%)
ANK repeat 271..301 CDD:293786
ANK repeat 303..334 CDD:293786
Ank_2 308..397 CDD:289560 8/23 (35%)
ANK repeat 336..367 CDD:293786
ANK repeat 369..400 CDD:293786 9/26 (35%)
Ank 402..432 CDD:278452 15/29 (52%)
ANK repeat 405..433 CDD:293786 15/27 (56%)
ANKYR 406..619 CDD:223738 85/212 (40%)
ANK 430..555 CDD:238125 50/124 (40%)
ANK repeat 435..466 CDD:293786 13/30 (43%)
ANK repeat 468..499 CDD:293786 15/30 (50%)
ANK repeat 501..532 CDD:293786 9/30 (30%)
ANK 529..654 CDD:238125 38/124 (31%)
ANK repeat 534..563 CDD:293786 13/28 (46%)
ANK repeat 568..598 CDD:293786 11/29 (38%)
ANK repeat 600..631 CDD:293786 9/30 (30%)
Ank_2 605..696 CDD:289560 20/95 (21%)
ANK repeat 633..661 CDD:293786 2/27 (7%)
ANK repeat 666..697 CDD:293786 9/35 (26%)
ANK 666..695 CDD:197603 8/33 (24%)
ANK 694..819 CDD:238125 3/9 (33%)
ANK repeat 699..730 CDD:293786 2/4 (50%)
Ank_2 704..795 CDD:289560
ANK repeat 732..763 CDD:293786
ANK repeat 765..796 CDD:293786
Ank_5 785..839 CDD:290568
ANK repeat 798..826 CDD:293786
ZU5 984..1088 CDD:128514
Death_ank1 1474..1557 CDD:260067
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4177
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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