DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3104 and Ankrd65

DIOPT Version :9

Sequence 1:	NP_001259969.1	Gene:	CG3104 / 33486	FlyBaseID:	FBgn0031473	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_001357751.1	Gene:	Ankrd65 / 242805	MGIID:	2685285	Length:	364	Species:	Mus musculus

Alignment Length:	350	Identity:	112/350 - (32%)
Similarity:	158/350 - (45%)	Gaps:	48/350 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KETPSD-----------VQLHMAAMRGDEVALLRVLDSGKVHVDCKDEDGTTPLILAAAGGHTYC 58
            :|.|:|           ..|..|...|....::::|..|. .|:.:|..|.|||.||...||...
Mouse    18 EEAPADKTERPLTSPGWSTLFQAVWWGAPSLVMQLLRQGS-SVEERDHTGRTPLHLAVMRGHAPL 81

  Fly    59 VMELLDQGADPNSRRLTGTTPLFFAAQGGHLDVVKILIKAGASVDTPSADGGTPLFVACQGGHVK 123
            |..||.:||...:...||.|||..||..||.:|.::|::.|||....|..|.|||..|...|...
Mouse    82 VRLLLQRGALAGAPDHTGRTPLHEAAWHGHSNVAELLLRRGASAAACSQTGLTPLHGAAALGRTL 146

  Fly   124 IVRELL---DCGANVNAHMKDRA--TPVFISAQNGHRTVLSLLIQAGAEIDIKRIDGATPLWIAA 183
            :|....   |.|::|    ||..  |....:|..|...||.|| .||...|   :|||  |.::|
Mouse   147 LVTSFTVASDSGSDV----KDVRGWTAAHWAAACGQLAVLELL-SAGGNAD---LDGA--LLVSA 201

  Fly   184 QMGQDHICKVLLQNGANVDTVRCDGATPLFKAAHKGHAAVITVLLKY--RPNLGQLPNGESALHA 246
            ..|.....::||..||.|||....|||.|..||..||...|.|||.:  .||:.. .|..||||.
Mouse   202 IAGSTSSLQLLLTLGAKVDTQDSTGATALGLAAGLGHHQDIEVLLDHGADPNIRD-RNNRSALHR 265

  Fly   247 AAMFGHMTVCKQLVAAGSDVLLKNHDGLTALQLAHQQKYTSICDYLQER---------------- 295
            ||..||:.|.:.|||.|.::..::..|||.|..|.:..:..:..:|.:|
Mouse   266 AATGGHLRVTQLLVAKGIEIDAQDSLGLTPLHHAARGGHVEVVSHLLDRGAHINAAGWLHKTPLH 330

  Fly   296 --IRTMVARSAKAMATSGVSSTVKT 318
              :....:.:.:.:.:.|.:||::|
Mouse   331 LAVENGHSTTVELLLSRGANSTLRT 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3104	NP_001259969.1	Ank_2	<13..72	CDD:289560	20/58 (34%)
		ANK repeat	13..40	CDD:293786	6/26 (23%)
		ANK	37..162	CDD:238125	47/129 (36%)
		ANK repeat	42..73	CDD:293786	13/30 (43%)
		Ank_2	47..137	CDD:289560	35/92 (38%)
		ANK repeat	75..106	CDD:293786	14/30 (47%)
		ANK	103..228	CDD:238125	46/129 (36%)
		ANK repeat	108..137	CDD:293786	10/31 (32%)
		Ank_2	113..202	CDD:289560	29/93 (31%)
		ANK repeat	141..171	CDD:293786	11/31 (35%)
		ANK	169..292	CDD:238125	47/124 (38%)
		ANK repeat	174..204	CDD:293786	12/29 (41%)
		Ank_2	179..270	CDD:289560	38/92 (41%)
		ANK repeat	207..237	CDD:293786	14/31 (45%)
		ANK repeat	239..270	CDD:293786	14/30 (47%)
Ankrd65	NP_001357751.1	ANK repeat	33..63	CDD:293786	6/30 (20%)
		PHA03095	49..>347	CDD:222980	102/309 (33%)
		ANK repeat	65..96	CDD:293786	13/30 (43%)
		ANK repeat	98..123	CDD:293786	11/24 (46%)
		ANK repeat	165..223	CDD:293786	23/63 (37%)
		ANK repeat	226..256	CDD:293786	14/29 (48%)
		ANK repeat	258..289	CDD:293786	14/30 (47%)
		ANK repeat	291..320	CDD:293786	7/28 (25%)
		ANK repeat	324..354	CDD:293786	3/29 (10%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4177
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53592
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910