DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3104 and Rnasel

DIOPT Version :9

Sequence 1:NP_001259969.1 Gene:CG3104 / 33486 FlyBaseID:FBgn0031473 Length:321 Species:Drosophila melanogaster
Sequence 2:NP_036012.1 Gene:Rnasel / 24014 MGIID:1098272 Length:735 Species:Mus musculus


Alignment Length:349 Identity:97/349 - (27%)
Similarity:149/349 - (42%) Gaps:55/349 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 TPS----------DVQLHMAAMRGDEVALLRVLDSGKVHVDCKDEDGTTPLILAAAGGHTYCVME 61
            |||          |..|..|..:||.|.:.::|:.|.....|:|..|.|||..|...|....|..
Mouse    13 TPSAGSQRTVVEDDSSLIKAVQKGDVVRVQQLLEKGADANACEDTWGWTPLHNAVQAGRVDIVNL 77

  Fly    62 LLDQGADPNSRRLTGTTPLFFAAQGGHLDVVKILIKAGASVDTPSADGGTPLFVACQGGHVKIVR 126
            ||..||||:.|:..|.||...|...|.:.:::||:..||.|:....:|.|....|.:.|:.:.:|
Mouse    78 LLSHGADPHRRKKNGATPFIIAGIQGDVKLLEILLSCGADVNECDENGFTAFMEAAERGNAEALR 142

  Fly   127 ELLDCGANVNAH---MKDR-------ATPVFISAQNGHRTVLSLLI-QAGAEIDIKRIDGATPL- 179
            .|...|||||..   .||:       ||.:..:|:.||..||.:|: ...||:|.:...|...| 
Mouse   143 FLFAKGANVNLRRQTTKDKRRLKQGGATALMSAAEKGHLEVLRILLNDMKAEVDARDNMGRNALI 207

  Fly   180 -----WIAAQMGQDHICKVLLQNGANVDTVRCDGATPLFKAAHKGHAAVITVLLKYRP-NLGQLP 238
                 |....:  :.|..:|:|:||:|:.....|.|||..|..:.|..::.:||.... |:....
Mouse   208 RTLLNWDCENV--EEITSILIQHGADVNVRGERGKTPLIAAVERKHTGLVQMLLSREGINIDARD 270

  Fly   239 N-GESALHAAAMFGHMTVCKQLVAAGSD-------VLLKNHD-GLTALQL--------------- 279
            | |::||..|.......:.:.|:..|:|       :..:||| .|..|.|               
Mouse   271 NEGKTALLIAVDKQLKEIVQLLLEKGADKCDDLVWIARRNHDYHLVKLLLPYVANPDTDPPAGDW 335

  Fly   280 -AHQQKYTSICDYLQERIRTMVAR 302
             .|..::.:....|....|.|:.:
Mouse   336 SPHSSRWGTALKSLHSMTRPMIGK 359

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3104NP_001259969.1 Ank_2 <13..72 CDD:289560 22/58 (38%)
ANK repeat 13..40 CDD:293786 8/26 (31%)
ANK 37..162 CDD:238125 46/134 (34%)
ANK repeat 42..73 CDD:293786 13/30 (43%)
Ank_2 47..137 CDD:289560 31/89 (35%)
ANK repeat 75..106 CDD:293786 10/30 (33%)
ANK 103..228 CDD:238125 39/141 (28%)
ANK repeat 108..137 CDD:293786 10/28 (36%)
Ank_2 113..202 CDD:289560 30/105 (29%)
ANK repeat 141..171 CDD:293786 12/37 (32%)
ANK 169..292 CDD:238125 34/154 (22%)
ANK repeat 174..204 CDD:293786 9/35 (26%)
Ank_2 179..270 CDD:289560 25/105 (24%)
ANK repeat 207..237 CDD:293786 9/30 (30%)
ANK repeat 239..270 CDD:293786 8/38 (21%)
RnaselNP_036012.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21 3/7 (43%)
ANK repeat 24..55 CDD:293786 8/30 (27%)
ANK 1 24..53 8/28 (29%)
Binding to TMEV Leader protein. /evidence=ECO:0000269|PubMed:29652922 26..51 8/24 (33%)
Ank_2 <29..88 CDD:403870 22/58 (38%)
ANK 2 58..87 13/28 (46%)
ANK repeat 59..89 CDD:293786 13/29 (45%)
Ank_2 61..>298 CDD:423045 72/238 (30%)
ANK repeat 91..122 CDD:293786 10/30 (33%)
ANK 3 91..120 10/28 (36%)
ANK repeat 124..154 CDD:293786 11/29 (38%)
ANK 4 124..153 10/28 (36%)
ANK repeat 167..199 CDD:293786 11/31 (35%)
ANK 5 167..197 10/29 (34%)
ANK 6 201..234 9/34 (26%)
2-5A binding (P-loop) 1 229..242 4/12 (33%)
ANK repeat 238..270 CDD:293786 9/31 (29%)
ANK 7 238..268 9/29 (31%)
2-5A binding (P-loop) 2 253..275 5/21 (24%)
ANK 8 272..301 7/28 (25%)
ANK repeat 272..297 CDD:293786 5/24 (21%)
ANK 9 303..328 6/24 (25%)
PKc_like 361..585 CDD:419665
RNase_RNase-L 588..707 CDD:199218
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 714..735
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4177
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

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