DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3104 and F26D2.10

DIOPT Version :9

Sequence 1:	NP_001259969.1	Gene:	CG3104 / 33486	FlyBaseID:	FBgn0031473	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_507152.2	Gene:	F26D2.10 / 180104	WormBaseID:	WBGene00009149	Length:	1213	Species:	Caenorhabditis elegans

Alignment Length:	262	Identity:	56/262 - (21%)
Similarity:	89/262 - (33%)	Gaps:	90/262 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 AGASVDTPSADGGTPLFVACQGGHVKIVRELLDCGANVNAHMKDRATPVFISAQNGHRTVLSLL- 161
            |..|::...|.|...|..:      |:.|::.:...:...|.        .|.::...||:||:
Worm   738 ANVSINLLQASGTDQLAAS------KVFRKIRELNLDFAKHE--------ASLKSASVTVISLIA 788

  Fly   162 ----IQAGAEIDI----KRIDGATPLWIAAQMGQDHIC--KVLL--------------------- 195
                |...::..|    |.||.:.| ||...:    ||  .:||
Worm   789 YYDEIFGNSKSKILTIEKHIDNSFP-WIYILL----ICIGSILLIGLFCVVAYGFTKNGRAKYTN 848

  Fly   196 ------------------------QNGAN--VDTVRCDGATPLFKAAHKGHAAVITVLLKYRPNL 234
                                    |:|.|  :|.||....|.:.||...|  :.||...|:
Worm   849 LYLYYFGKPLDYERRWRYSLFLDNQDGKNTLLDAVREINKTNVMKAVKLG--SYITAYNKF---- 907

  Fly   235 GQLPNGESALHAAAMFGHMTVCKQLVAAGSDVLLKNHDGLTALQLAHQQKYTSICDYLQ--ERIR 297
                 |.:|||||.......:.|.|:..|:|:.|.|....|..|:.......:..|.::  |:||
Worm   908 -----GNTALHAATKSALPEIVKILIEHGADLTLLNTLNKTPEQMIPLDSPDNSKDKIEKLEKIR 967

  Fly   298 TM 299
            .:
Worm   968 KL 969

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3104	NP_001259969.1	Ank_2	<13..72	CDD:289560
		ANK repeat	13..40	CDD:293786
		ANK	37..162	CDD:238125	13/68 (19%)
		ANK repeat	42..73	CDD:293786
		Ank_2	47..137	CDD:289560	7/38 (18%)
		ANK repeat	75..106	CDD:293786	2/7 (29%)
		ANK	103..228	CDD:238125	35/182 (19%)
		ANK repeat	108..137	CDD:293786	4/28 (14%)
		Ank_2	113..202	CDD:289560	24/146 (16%)
		ANK repeat	141..171	CDD:293786	7/38 (18%)
		ANK	169..292	CDD:238125	39/175 (22%)
		ANK repeat	174..204	CDD:293786	12/78 (15%)
		Ank_2	179..270	CDD:289560	30/139 (22%)
		ANK repeat	207..237	CDD:293786	7/29 (24%)
		ANK repeat	239..270	CDD:293786	11/30 (37%)
F26D2.10	NP_507152.2	WSN	28..95	CDD:197734
		Ank_2	<870..938	CDD:289560	24/78 (31%)
		ANK	872..>944	CDD:238125	25/82 (30%)
		ANK repeat	874..905	CDD:293786	11/32 (34%)
		ANK repeat	907..938	CDD:293786	11/39 (28%)
		BRCT	983..1063	CDD:214602
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4177
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900