DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3104 and ASB12

DIOPT Version :9

Sequence 1:NP_001259969.1 Gene:CG3104 / 33486 FlyBaseID:FBgn0031473 Length:321 Species:Drosophila melanogaster
Sequence 2:NP_569059.3 Gene:ASB12 / 142689 HGNCID:19763 Length:318 Species:Homo sapiens


Alignment Length:229 Identity:72/229 - (31%)
Similarity:107/229 - (46%) Gaps:35/229 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 KKETPSDVQ----LHMAAMRGDEVALLRVL--DSGKVHVDCKDEDGT--TPLILAAAGGHTYCVM 60
            |:|..:|.:    |:.|....|...|.::|  :..|..::.:...|.  |||.|||:.||..|:.
Human    26 KEEEDTDTEEKQALNQAVYDNDSYTLDQLLRQERYKRFINSRSGWGVPGTPLRLAASYGHLSCLQ 90

  Fly    61 ELLDQGADPNSRRLTGTTPLFFAAQGGHLDVVKILIKAGASVDTPSADGGTPLFVACQGGHVKIV 125
            .||..|||.:|..:...||||.|...||||.|::|::||||......:..:|:..|.:.|.|.|:
Human    91 VLLAHGADVDSLDVKAQTPLFTAVSHGHLDCVRVLLEAGASPGGSIYNNCSPVLTAARDGAVAIL 155

  Fly   126 RELLDCGANVNAHMK---------DRATPVFISAQNGHRTVLSLLIQAGAEIDIKRIDGA----- 176
            :||||.||..|...|         ..:.|::::|..||.....||:..||:.|....|..     
Human   156 QELLDHGAEANVKAKLPVWASNIASCSGPLYLAAVYGHLDCFRLLLLHGADPDYNCTDQGLLARV 220

  Fly   177 ----TPLWIAAQMGQDHIC-----KVLLQNGANV 201
                |.|.|...    |.|     ::|:..|||:
Human   221 PRPRTLLEICLH----HNCEPEYIQLLIDFGANI 250

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3104NP_001259969.1 Ank_2 <13..72 CDD:289560 21/62 (34%)
ANK repeat 13..40 CDD:293786 6/28 (21%)
ANK 37..162 CDD:238125 49/135 (36%)
ANK repeat 42..73 CDD:293786 16/32 (50%)
Ank_2 47..137 CDD:289560 39/89 (44%)
ANK repeat 75..106 CDD:293786 15/30 (50%)
ANK 103..228 CDD:238125 32/122 (26%)
ANK repeat 108..137 CDD:293786 11/28 (39%)
Ank_2 113..202 CDD:289560 31/112 (28%)
ANK repeat 141..171 CDD:293786 9/29 (31%)
ANK 169..292 CDD:238125 11/47 (23%)
ANK repeat 174..204 CDD:293786 10/42 (24%)
Ank_2 179..270 CDD:289560 8/28 (29%)
ANK repeat 207..237 CDD:293786
ANK repeat 239..270 CDD:293786
ASB12NP_569059.3 Ank_2 8..103 CDD:289560 25/76 (33%)
ANK 75..201 CDD:238125 48/125 (38%)
ANK repeat 75..103 CDD:293786 15/27 (56%)
Ank_2 77..168 CDD:289560 40/90 (44%)
ANK repeat 105..136 CDD:293786 15/30 (50%)
ANK repeat 138..168 CDD:293786 12/29 (41%)
ANK repeat 182..208 CDD:293786 8/25 (32%)
ANK 184..>250 CDD:238125 18/69 (26%)
Ank_2 185..>250 CDD:289560 17/68 (25%)
SOCS_box 277..315 CDD:284857
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24120
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
22.010

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