DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3117 and prss60.2

DIOPT Version :9

Sequence 1:	NP_608722.2	Gene:	CG3117 / 33484	FlyBaseID:	FBgn0031471	Length:	347	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	268	Identity:	79/268 - (29%)
Similarity:	131/268 - (48%)	Gaps:	38/268 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 NALDGSPQVFGDQTKPNQFPWVTALFAK--GSYLGGGSLITPGLVLTAAHILAGLSPNDIMVRAG 147
            ||.:||            :||..:|.:.  |.:..|||||:...||||||.|.|:|.:.::|..|
Zfish    39 NAPEGS------------WPWQVSLQSPRYGGHFCGGSLISSEWVLTAAHCLPGVSESSLVVYLG 91

  Fly   148 EWDLSSSEKLNP-PMDRQVIKIMEHEAFNYSSGANDLALLFLDSPFELRANIQTIRLPIPDKTFD 211
            .   .:.:.:|. ...|.|.||:.|.::|.::..||:|||.|.|.......|:.:.|...:..:.
Zfish    92 R---RTQQGVNTHETSRNVAKIIVHSSYNSNTNDNDIALLRLSSAVTFNDYIRPVCLAAQNSVYS 153

  Fly   212 RRICT-VAGWG-MRSSTDVDIQTIQQKVDLPVVESSKCQRQLRLTKMGSNYQLPASLMCAG-GEE 273
            ....: :.||| :::..::....|.|:..:|||.:.:|..||....:.:|      ::||| .:.
Zfish   154 AGTSSWITGWGDVQAGVNLPAPGILQETMIPVVANDRCNAQLGSGTVTNN------MICAGLAKG 212

  Fly   274 GRDVCSLFGGFAL---FCSLDDDPNRYEQAGIVSFGVGCGQANVPTTFTHVSKFMEWINPHLEQV 335
            |:|.|....|..:   .|::      :.||||.|:|.||...|.|..:|.||::..||:..:.|
Zfish   213 GKDTCQGDSGGPMVTRLCTV------WIQAGITSWGYGCADPNSPGVYTRVSQYQSWISSKISQ- 270

  Fly   336 LSVPGNML 343
             :.||.:|
Zfish   271 -NQPGFIL 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3117	NP_608722.2	Tryp_SPc	95..329	CDD:238113	70/242 (29%)
CG3117	NP_608722.2	Tryp_SPc	95..328	CDD:214473	69/241 (29%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	73/251 (29%)
		Tryp_SPc	34..267	CDD:238113	75/254 (30%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587618
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840